Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
| ▸ | CTSK | P43235 | 8/20 | 0.47 |
| ▸ | CTSS | P25774 | 4/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6407054 | 0.92 | CTSK (0.53) | ATMCTSKCTSSSYKCA12 | |
| SCHEMBL272612 | 0.85 | ATM (0.62) | ATMCTSKCTSSSYKCA12 | |
| SCHEMBL272610 | 0.85 | ATM (0.62) | ATMCTSKCTSSSYKCA12 | |
| SCHEMBL272611 | 0.85 | ATM (0.62) | ATMCTSKCTSSSYKCA12 | |
| SCHEMBL28448310 | 0.83 | ATM (0.64) | ATMCTSKCTSSSYKCTSL | |
| SCHEMBL17849935 | 0.83 | MAPT (0.57) | ATMCTSSSYKCA1PPARA | |
| SCHEMBL20358567 | 0.83 | SYK (0.60) | SYKCA1MAPT | |
| SCHEMBL20358568 | 0.83 | SYK (0.60) | SYKCA1MAPT | |
| SCHEMBL15716286 | 0.82 | PPARA (0.58) | ATMCTSKCTSSSYKCA12 | |
| SCHEMBL8194405 | 0.82 | PPARA (0.58) | ATMCTSKCTSSSYKCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010091104-A1 | GLUCOSYLCERAMIDE SYNTHASE INHIBITORS | EXELIXIS, INC. (US) | 2010-08-12 | — | — | WO | disclosed |