Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.63 |
| ▸ | CTSS | P25774 | 1/20 | 0.60 |
| ▸ | PPARG | P37231 | 1/20 | 0.58 |
| ▸ | UGCG | Q16739 | 13/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | KLK7 | P49862 | 2/20 | 0.53 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2538853 | 0.89 | PPARA (0.60) | PPARACTSSPPARGKLK7KLK5 | |
| SCHEMBL2538849 | 0.89 | PPARA (0.60) | PPARACTSSPPARGKLK7KLK5 | |
| SCHEMBL3746299 | 0.88 | PPARA (0.62) | PPARACTSSPPARGUGCGKLK7 | |
| SCHEMBL13291363 | 0.87 | KMT2A (0.64) | CTSSUGCGCYP3A4KMT2A | |
| SCHEMBL27340724 | 0.87 | KMT2A (0.64) | CTSSUGCGCYP3A4KMT2A | |
| SCHEMBL6582704 | 0.86 | PPARA (0.59) | PPARACTSSPPARGKLK7KLK5 | |
| SCHEMBL6582608 | 0.85 | PPARA (0.60) | PPARACTSSPPARGKLK7KLK5 | |
| SCHEMBL6582611 | 0.85 | PPARA (0.60) | PPARACTSSPPARGKLK7KLK5 | |
| SCHEMBL9090868 | 0.83 | TACR1 (0.60) | PPARACTSSPPARGUGCGCYP3A4 | |
| SCHEMBL9090873 | 0.83 | TACR1 (0.60) | PPARACTSSPPARGUGCGCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010091104-A1 | GLUCOSYLCERAMIDE SYNTHASE INHIBITORS | EXELIXIS, INC. (US) | 2010-08-12 | — | — | WO | disclosed |