Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.33 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.33 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 3/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5662679 | 0.99 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2ASMN1; SMN2DPP4 | |
| Hydrochloric Acid SCHEMBL5664658 | 0.99 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2ASMN1; SMN2DPP4 | |
| SCHEMBL2891954 | 0.83 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2ASMN1; SMN2DPP4 | |
| SCHEMBL5988553 | 0.83 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2ASMN1; SMN2DPP4 | |
| SCHEMBL2891956 | 0.83 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2ASMN1; SMN2DPP4 | |
| SCHEMBL5664620 | 0.81 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5664623 | 0.81 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2889524 | 0.78 | IDO1 (0.40) | ALDH1A1MEN1KMT2ASMN1; SMN2NR3C1 | |
| SCHEMBL13199544 | 0.77 | ABCB1 (0.41) | ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2889416 | 0.76 | KCNA5 (0.47) | ALDH1A1MEN1KMT2ASMN1; SMN2NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1718629-B1 | Benzopyran compounds useful for the treatment of arrhytmia | NISSAN CHEMICAL IND LTD (JP) | 2012-12-26 | — | — | EP | disclosed |
| US-7781483-B2 | Benzopyran compound | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2010-08-24 | — | — | US | disclosed |