Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YARS1 | P54577 | 2/20 | 0.59 |
| ▸ | OPRD1 | P41143 | 8/20 | 0.52 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | CTSC | P53634 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL179024 | 0.89 | YARS1 (0.73) | YARS1OPRD1SLC7A5OPRM1OPRK1 | |
| SCHEMBL29615665 | 0.83 | OPRD1 (0.59) | YARS1OPRD1SLC7A5OPRM1OPRK1 | |
| SCHEMBL30946748 | 0.80 | YARS1 (0.60) | YARS1SLC7A5CTSC | |
| SCHEMBL29697023 | 0.80 | YARS1 (0.60) | YARS1OPRD1SLC7A5OPRM1OPRK1 | |
| SCHEMBL13979586 | 0.79 | CTSC (0.57) | YARS1SLC7A5CTSC | |
| SCHEMBL13538435 | 0.79 | CTSC (0.57) | YARS1SLC7A5CTSC | |
| Phenylalanyltyrosine SCHEMBL4282059 | 0.77 | MME (0.67) | OPRD1SLC7A5OPRM1OPRK1 | |
| Phenylalanyltyrosine SCHEMBL3037096 | 0.77 | MME (0.67) | OPRD1SLC7A5OPRM1OPRK1 | |
| SCHEMBL8695556 | 0.77 | MME (0.67) | OPRD1SLC7A5OPRM1OPRK1 | |
| Phenylalanyltyrosine SCHEMBL31255162 | 0.77 | MME (0.67) | OPRD1SLC7A5OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010096170-A2 | INHIBITION OF TRNA SYNTHETASES AND THERAPEUTIC APPLICATIONS THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2010-08-26 | — | — | WO | disclosed |