Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13201265 | 0.87 | POLB (0.38) | POLBCYP2C19CYP1A2CYP2C9CASP3 | |
| SCHEMBL13201217 | 0.84 | POLB (0.46) | POLBCYP2C19CYP1A2CYP2C9CASP3 | |
| SCHEMBL13294095 | 0.78 | CYP1A2 (0.35) | POLBCYP2C19CYP1A2CYP2C9CASP3 | |
| SCHEMBL13201245 | 0.78 | CYP1A2 (0.35) | POLBCYP2C19CYP1A2CYP2C9CASP3 | |
| SCHEMBL13201220 | 0.73 | NPSR1 (0.32) | POLBNPSR1 | |
| SCHEMBL13201211 | 0.73 | NPSR1 (0.32) | POLBNPSR1 | |
| SCHEMBL14409134 | 0.73 | NPSR1 (0.32) | POLBNPSR1 | |
| SCHEMBL13928082 | 0.68 | NPSR1 (0.32) | POLBCYP2C19CYP1A2CYP2C9NPSR1 | |
| SCHEMBL21744319 | 0.67 | CYP1A2 (0.45) | CYP2C19CYP1A2CYP2C9CASP3MMP1 | |
| SCHEMBL4743617 | 0.66 | CYP1A2 (0.53) | CYP2C19CYP1A2CYP2C9NPSR1MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7772341-B2 | Norbornene compounds with cross-linkable groups and their derivatives | NATIONAL TAIWAN UNIVERSITY OF SCIENCE & TECHNOLOGY (TW) | 2010-08-10 | — | — | US | disclosed |
| US-7271230-B2 | Norbornene compounds with cross-linkable groups and their derivatives | NATIONAL TAIWAN UNIVERSITY OF SCIENCE & TECHNOLOGY (TW) | 2007-09-18 | — | — | US | disclosed |
| US-20070073017-A1 | Norbornene compounds with cross-linkable groups and their derivatives | LIAW DER-JANG | 2007-03-29 | — | — | US | disclosed |