Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | MMP3 | P08254 | 2/20 | 0.39 |
| ▸ | MMP9 | P14780 | 2/20 | 0.39 |
| ▸ | MMP13 | P45452 | 2/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13201265 | 0.86 | POLB (0.38) | POLBCASP3NPSR1CYP2C19CYP1A2 | |
| SCHEMBL13201153 | 0.84 | POLB (0.36) | POLBCASP3NPSR1CYP2C19CYP1A2 | |
| SCHEMBL13201245 | 0.81 | CYP1A2 (0.35) | POLBCASP3NPSR1CYP2C19CYP1A2 | |
| SCHEMBL13294095 | 0.81 | CYP1A2 (0.35) | POLBCASP3NPSR1CYP2C19CYP1A2 | |
| SCHEMBL21744319 | 0.77 | CYP1A2 (0.45) | CASP3CYP2C19CYP1A2CYP2C9MMP2 | |
| SCHEMBL4743617 | 0.76 | CYP1A2 (0.53) | NPSR1CYP2C19CYP1A2CYP2C9MMP2 | |
| SCHEMBL14159952 | 0.72 | L3MBTL1 (0.38) | CYP2C19CYP1A2CYP2C9ALDH1A1TP53 | |
| SCHEMBL27415448 | 0.72 | CYP1A2 (0.49) | NPSR1CYP2C19CYP1A2CYP2C9MMP2 | |
| SCHEMBL5050954 | 0.69 | CA12 (0.49) | NPSR1CYP2C19CYP1A2CYP2C9MMP2 | |
| SCHEMBL30096658 | 0.69 | CA12 (0.49) | NPSR1CYP2C19CYP1A2CYP2C9MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7772341-B2 | Norbornene compounds with cross-linkable groups and their derivatives | NATIONAL TAIWAN UNIVERSITY OF SCIENCE & TECHNOLOGY (TW) | 2010-08-10 | — | — | US | disclosed |
| US-7728090-B2 | Norbornene compounds with cross-linkable groups and their derivatives | NATIONAL TAIWAN UNIVERSITY OF SCIENCE & TECHNOLOGY (TW) | 2010-06-01 | — | — | US | disclosed |
| US-20100087659-A1 | NORBORNENE COMPOUNDS WITH CROSS-LINKABLE GROUPS AND THEIR DERIVATIVES | LIAW DER-JANG | 2010-04-08 | — | — | US | disclosed |
| US-7323518-B2 | Norbornene compounds with cross-linkable groups and their derivatives | NATIONAL TAIWAN UNIVERSITY OF SCIENCE & TECHNOLOGY (TW) | 2008-01-29 | — | — | US | disclosed |
| US-7309751-B2 | Norbornene compounds with cross-linkable groups and their derivatives | NATIONAL TAIWAN UNIVERSITY OF SCIENCE & TECHNOLOGY (TW) | 2007-12-18 | — | — | US | disclosed |
| US-7271223-B2 | Norbomene compounds with cross-linkable groups and their derivatives | NATIONAL TAIWAN UNIVERSITY OF SCIENCE & TECHNOLOGY (TW) | 2007-09-18 | — | — | US | disclosed |
| US-7271230-B2 | Norbornene compounds with cross-linkable groups and their derivatives | NATIONAL TAIWAN UNIVERSITY OF SCIENCE & TECHNOLOGY (TW) | 2007-09-18 | — | — | US | disclosed |
| US-20070073018-A1 | Norbornene compounds with cross-linkable groups and their derivatives | LIAW DER-JANG | 2007-03-29 | — | — | US | disclosed |
| US-20070073079-A1 | Norbornene compounds with cross-linkable groups and their derivatives | LIAW DER-JANG | 2007-03-29 | — | — | US | disclosed |
| US-20070073080-A1 | Norbornene compounds with cross-linkable groups and their derivatives | LIAW DER-JANG | 2007-03-29 | — | — | US | disclosed |
| US-20070073017-A1 | Norbornene compounds with cross-linkable groups and their derivatives | LIAW DER-JANG | 2007-03-29 | — | — | US | disclosed |
| US-20070066774-A1 | Norbornene compounds with cross-linkable groups and their derivatives | LIAW DER-JANG | 2007-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070073080-A1 | Norbornene compounds with cross-linkable groups and their derivatives | OXER1, SQLE, ALOX12 | POLB 2246/4885CASP3 762/4885NPSR1 2394/4885 |
| US-20070073079-A1 | Norbornene compounds with cross-linkable groups and their derivatives | OXER1, SQLE, ALOX12 | POLB 2246/4885CASP3 762/4885NPSR1 2394/4885 |
| US-20100087659-A1 | NORBORNENE COMPOUNDS WITH CROSS-LINKABLE GROUPS AND THEIR DERIVATIVES | SQLE, OXER1, MACF1 | POLB 2396/4885CASP3 987/4885NPSR1 2920/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.