SCHEMBL13201178

SCHEMBL13201178

OCc1cc([C@@H]2O[C@H](COCc3ccccc3)[C@@H](OCc3ccccc3)[C@H](OCc3ccccc3)[C@H]2OCc2ccccc2)c(OCc2ccccc2)cc1F

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 9/20 0.41
CDC25B P30305 8/20 0.41
SSTR1 P30872 1/20 0.40
SSTR2 P30874 1/20 0.40
SSTR4 P31391 1/20 0.40
SSTR3 P32745 1/20 0.40
SSTR5 P35346 1/20 0.40
PTPN2 P17706 5/20 0.40
PTPN11 Q06124 5/20 0.40
PTPN6 P29350 4/20 0.40
HTR1A P08908 1/20 0.39
NT5E P21589 1/20 0.39
TP53 P04637 1/20 0.38
MDM2 Q00987 1/20 0.38
TACR2 P21452 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12425666 1.00 PTPN1 (0.41) PTPN1CDC25BSSTR1SSTR2SSTR4
SCHEMBL20140122 0.85 SLC5A1 (0.42) PTPN1CDC25BSSTR1SSTR2SSTR4
SCHEMBL13201199 0.84 SSTR1 (0.39) PTPN1CDC25BSSTR1SSTR2SSTR4
SCHEMBL12425689 0.84 SSTR1 (0.39) PTPN1CDC25BSSTR1SSTR2SSTR4
SCHEMBL12425833 0.84 SLC5A2 (0.39) PTPN1CDC25BSSTR1SSTR2SSTR4
SCHEMBL2575933 0.82 HTR1A (0.45) PTPN1CDC25BSSTR1SSTR2SSTR4
SCHEMBL14590075 0.81 PTPN1 (0.44) PTPN1CDC25BSSTR1SSTR2SSTR4
SCHEMBL12425663 0.81 BCHE (0.38) PTPN1CDC25BSSTR1SSTR2SSTR4
SCHEMBL13201168 0.81 BCHE (0.38) PTPN1CDC25BSSTR1SSTR2SSTR4
SCHEMBL19665070 0.81 PTPN1 (0.45) PTPN1CDC25BPTPN2PTPN11PTPN6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7772407-B2 C-glycoside derivatives and salts thereof ASTELLAS PHARMA INC. (JP) 2010-08-10 US disclosed
US-20070161787-A1 C-glycoside derivatives and salts thereof ASTELLAS PHARMA INC. (JP) 2007-07-12 US disclosed
US-7202350-B2 C-glycoside derivatives and salts thereof ASTELLAS PHARMA INC. (JP) 2007-04-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070161787-A1 C-glycoside derivatives and salts thereof SLC5A1, SLC5A2, SLC2A1 PTPN1 224/4885CDC25B 4395/4885SSTR1 650/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.