Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | LIPE | Q05469 | 2/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8327339 | 0.85 | EPHX2 (0.45) | EPHX2MEN1KMT2AAKR1C3 | |
| SCHEMBL2969395 | 0.81 | TDP1 (0.41) | MEN1KMT2AMMP2L3MBTL1 | |
| SCHEMBL8327403 | 0.81 | TDP1 (0.41) | L3MBTL1 | |
| SCHEMBL8320723 | 0.81 | PSEN1 (0.43) | EPHX2MEN1KMT2AMMP9MMP2 | |
| SCHEMBL8320725 | 0.81 | EPHX2 (0.42) | EPHX2AKR1C3L3MBTL1 | |
| SCHEMBL8320747 | 0.81 | TDP1 (0.41) | MEN1KMT2AMMP2L3MBTL1 | |
| SCHEMBL2953994 | 0.81 | ACHE (0.54) | EPHX2MEN1KMT2AAKR1C3MMP2 | |
| SCHEMBL2964063 | 0.81 | PSEN1 (0.43) | EPHX2MEN1KMT2AMMP9MMP2 | |
| SCHEMBL8326043 | 0.80 | ACHE (0.56) | EPHX2 | |
| SCHEMBL13480219 | 0.80 | ACHE (0.56) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7772270-B2 | Imino acid derivatives as inhibitors of matrix metalloproteinases | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2010-08-10 | — | — | US | disclosed |
| US-7772270-B2 | Imino acid derivatives as inhibitors of matrix metalloproteinases | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2010-08-10 | — | — | US | disclosed |
| EP-1585728-B1 | IMINO ACID DERIVATIVES FOR USE AS INHIBITORS OF MATRIX METALLOPROTEINASES | SANOFI AVENTIS DEUTSCHLAND (DE) | 2010-02-24 | — | — | EP | disclosed |