SCHEMBL132013

SCHEMBL132013

c1cc(C2=NCCO2)ccc1C1=NCCO1

nearest known ligand 0.61

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 1/20 0.49
HRH3 Q9Y5N1 1/20 0.49
LTA4H P09960 1/20 0.47
LSS P48449 1/20 0.40
KCNN4 O15554 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
USP9X Q93008 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10520360 0.91 KCNH2 (0.48) KCNH2HRH3LTA4HLSSKCNN4
SCHEMBL9475161 0.91 KCNH2 (0.44) KCNH2HRH3LTA4HLSSKCNN4
SCHEMBL20410837 0.91 KCNH2 (0.44) KCNH2HRH3LTA4HLSSSMN1; SMN2
SCHEMBL961792 0.89 KCNN4 (0.44) KCNH2HRH3LTA4HKCNN4SMN1; SMN2
SCHEMBL1856955 0.89 NPC1 (0.43) KCNH2HRH3LTA4HLSSSMN1; SMN2
SCHEMBL1817200 0.89 LSS (0.51) KCNH2HRH3LTA4HLSS
SCHEMBL20410952 0.89 KCNH2 (0.43) KCNH2HRH3LTA4HLSSKCNN4
SCHEMBL5464687 0.89 NPC1 (0.43) KCNH2HRH3LTA4HLSSSMN1; SMN2
SCHEMBL9181791 0.89 KCNH2 (0.43) KCNH2HRH3LTA4HLSSKCNN4
SCHEMBL17677999 0.89 KCNH2 (0.43) KCNH2HRH3LTA4HLSSSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2400 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122013347-A High-quality copolymerized flame-retardant nylon 66 fiber and preparation method thereof 浙江理工大学 2026-05-12 CN claimed
US-12428525-B2 Thermoplastic composition made from a polyamide polymer obtained from a prepolymer and a chain extender and manufacturing method ARKEMA FRANCE (FR) 2025-09-30 US claimed
US-12428551-B2 Chemically compatibilized fluoropolymer blends DAIKIN AMERICA, INC. (US) 2025-09-30 US claimed
CN-116209685-B Reactive fluoropolymer compatibilizers and uses thereof 大金美国股份有限公司 2025-06-03 CN claimed
WO-2025089272-A1 LIGHT CONTROL SHEET, LIGHT CONTROL DEVICE AND METHOD FOR PRODUCING LIGHT CONTROL SHEET TOPPANホールディングス株式会社 2025-05-01 WO claimed
CN-119899581-A Degradable self-healing protective coating based on nanotechnology and preparation method thereof 瑞德浩特(海南)企业管理有限公司 2025-04-29 CN claimed
CN-119708874-A Liquid crystal polymer particles, liquid crystal polymer film and preparation method thereof 浙江聚领新材料有限公司 2025-03-28 CN claimed
US-12258471-B2 Readily process-able, oil-resistant thermoplastic vulcanizates PARKER-HANNIFIN CORPORATION (US) 2025-03-25 US claimed
US-12252572-B2 Method for improving adhesion in and between layers of additive manufactured articles LUMAS POLYMERS LLC (US) 2025-03-18 US claimed
CN-118879043-A Formula and process method for producing PET (polyethylene terephthalate) nucleation master batch suitable for supercritical physical foaming 维赛(江苏)复合材料科技有限公司 2024-11-01 CN claimed
US-4806267-A Liquid aromatic bisoxazoline and bisoxazine monomer mixtures and process for crosslinking using phenolics ASHLAND OIL, INC. (US) 1989-02-21 US claimed
US-4739032-A Aromatic oligomers and resins IMPERIAL CHEMICAL INDUSTRIES PLC 1988-04-19 US claimed
US-4731398-A POLYESTER, POLYOXAZOLINE, ACRYLATE DYNAMIT NOBEL AG (DE) 1988-03-15 US claimed
EP-0149837-B1 HEAT HARDENABLE ADHESIVE AND CEMENT HÜLS TROISDORF AKTIENGESELLSCHAFT (DE) 1988-03-02 EP claimed
EP-0250715-A1 Resins from phenolics and oxazolines using phosphorous acid esters as catalysts Ashland Oil, Inc. (US) 1988-01-07 EP claimed
US-4699970-A Resin from phenolic and oxazoline using phosphorous acid ester as catalyst ASHLAND OIL, INC. (US) 1987-10-13 US claimed
EP-0222165-A2 Heat-curable adhesive and sealing compounds HÜLS AKTIENGESELLSCHAFT (DE) 1987-05-20 EP claimed
EP-0215239-A1 Improved process for preparing poly(ether-amide)polymeric compositions Ashland Oil, Inc. (US) 1987-03-25 EP claimed
US-4613662-A Process for catalytic preparation of poly(ether-amide) polymeric composition from oxazoline and polyphenol ASHLAND OIL, INC. (US) 1986-09-23 US claimed
US-4562225-A BLEND OF POLYESTERE AND POLYOXAZOLINES DYNAMIT NOBEL AG (DE) 1985-12-31 US claimed