⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4920480 | 0.67 | — | — | |
| SCHEMBL2867175 | 0.64 | ALDH1A1 (0.46) | — | |
| SCHEMBL2875131 | 0.64 | KDM4E (0.46) | — | |
| SCHEMBL9045356 | 0.64 | ALDH1A1 (0.30) | — | |
| SCHEMBL132014 | 0.64 | — | — | |
| SCHEMBL9582 | 0.64 | — | — | |
| SCHEMBL7491987 | 0.60 | CDK1 (0.33) | — | |
| SCHEMBL838220 | 0.58 | — | — | |
| SCHEMBL940153 | 0.57 | — | — | |
| Purine SCHEMBL30862524 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 925 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11993590-B2 | Pyranone compounds useful to modulate OMA1 protease | 712 NORTH INC. (US) | 2024-05-28 | — | — | US | claimed |
| US-20230321049-A1 | COMPOSITIONS OF ENPP1 INHIBITORS AND USES THEREOF | Petragen, Inc. | 2023-10-12 | — | — | US | claimed |
| WO-2023107490-A1 | HETEROCYCLE-CONTAINING LONP1 INHIBITOR COMPOUNDS, USES AND METHODS | PRETZEL THERAPEUTICS, INC. (US) | 2023-06-15 | — | — | WO | claimed |
| US-20210246125-A1 | PYRANONE COMPOUNDS USEFUL TO MODULATE OMA1 PROTEASE | 712 NORTH INC. | 2021-08-12 | — | — | US | claimed |
| CN-111320630-A | Compound with TNF- α inhibitory activity and application | 武汉华杰世纪生物医药有限公司 | 2020-06-23 | — | — | CN | claimed |
| CN-110669058-A | Tricyclic quinolone carboxylic acid and preparation method thereof | 江西农业大学 | 2020-01-10 | — | — | CN | claimed |
| US-10294260-B2 | Tetracyclic anthraquinone derivatives | TIANJIN HEMAY ONCOLOGY PHARMACEUTICAL CO., LTD. (CN) | 2019-05-21 | — | — | US | claimed |
| EP-3283481-B1 | CHROMENE DERIVATIVES AS PHOSHOINOSITIDE 3-KINASES INHIBITORS | CHIESI FARM SPA (IT) | 2019-03-13 | — | — | EP | claimed |
| US-10179790-B2 | MTH1 inhibitors for treatment of cancer | THOMAS HELLEDAYS STIFTELSE FOR MEDICINSK FORSKNING (SE) | 2019-01-15 | — | — | US | claimed |
| US-9968604-B2 | Chromene derivatives as phoshoinositide 3-kinases inhibitors | CHIESI FARMACEUTICI S.P.A. (IT) | 2018-05-15 | — | — | US | claimed |
| EP-0154528-B1 | ALKENE, ALKYNE OR CYCLOALKYLENE DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-12-11 | — | — | EP | claimed |
| EP-0421600-A1 | Asymmetric chemical synthesis and intermediates for making antifungal compounds | SCHERING CORPORATION (US) | 1991-04-10 | — | — | EP | claimed |
| WO-1991003473-A1 | THREONINE DERIVED ASYMMETRIC CHEMICAL SYNTHESIS AND INTERMEDIATES FOR MAKING ANTIFUNGAL COMPOUNDS | SCHERING CORPORATION (US) | 1991-03-21 | — | — | WO | claimed |
| WO-1991003451-A1 | ASYMMETRIC CHEMICAL SYNTHESIS AND INTERMEDIATES FOR MAKING ANTIFUNGAL COMPOUNDS | SCHERING CORPORATION (US) | 1991-03-21 | — | — | WO | claimed |
| EP-0415748-A1 | Threonine derived asymmetric chemical synthesis and intermediates for making antifungal compounds | SCHERING CORPORATION (US) | 1991-03-06 | — | — | EP | claimed |
| US-4956369-A | HYPOTENSIVE AGENTS | BOEHRINGER BIOCHEMIA ROBIN S.P.A. (IT) | 1990-09-11 | — | — | US | claimed |
| US-4873329-A | ANTIANDROGENS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-10-10 | — | — | US | claimed |
| EP-0301422-A2 | Thiomethyl and sulfinylmethyl derivatives having gastric acid antisecretory activity, processes for the preparation thereof and pharmaceutical compositions containing them | CHIESI FARMACEUTICI S.p.A. (IT) | 1989-02-01 | — | — | EP | claimed |
| EP-0214479-A2 | Benzimidazol-2-ylpyridinium compounds | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1987-03-18 | — | — | EP | claimed |
| EP-0154528-A2 | Alkene, alkyne or cycloalkylene derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-09-11 | — | — | EP | claimed |