Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8235379 | 0.86 | ADAM17 (0.68) | ADAM17TNF | |
| SCHEMBL13200425 | 0.85 | ADAM17 (0.67) | ADAM17TNF | |
| SCHEMBL13200205 | 0.85 | TNF (0.74) | ADAM17TNF | |
| SCHEMBL8235427 | 0.84 | ADAM17 (0.76) | ADAM17TNF | |
| SCHEMBL13200567 | 0.84 | ADAM17 (0.76) | ADAM17TNF | |
| SCHEMBL13201311 | 0.83 | ADAM17 (0.74) | ADAM17TNF | |
| SCHEMBL13200801 | 0.83 | TNF (0.78) | ADAM17TNF | |
| SCHEMBL13218946 | 0.83 | ADAM17 (0.65) | ADAM17 | |
| SCHEMBL13218737 | 0.83 | ADAM17 (0.87) | ADAM17TNF | |
| SCHEMBL8227024 | 0.83 | ADAM17 (1.00) | ADAM17TNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7772263-B2 | Compounds for the treatment of inflammatory disorders | SCHERING CORPORATION (US) | 2010-08-10 | — | — | US | disclosed |