Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 15/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2974995 | 0.87 | — | — | |
| SCHEMBL2970877 | 0.87 | — | — | |
| SCHEMBL2970879 | 0.87 | — | — | |
| SCHEMBL7252349 | 0.86 | SCN9A (0.37) | SCN9ADHODH | |
| SCHEMBL4065246 | 0.86 | SCN9A (0.42) | SCN9A | |
| SCHEMBL9587280 | 0.85 | LMNA (0.35) | LMNATHRBSMN1; SMN2DHODH | |
| SCHEMBL26942159 | 0.85 | DHODH (0.33) | LMNATHRBSMN1; SMN2DHODH | |
| SCHEMBL26942162 | 0.85 | DHODH (0.33) | LMNATHRBSMN1; SMN2DHODH | |
| SCHEMBL2976874 | 0.85 | DHODH (0.33) | LMNATHRBSMN1; SMN2DHODH | |
| SCHEMBL2966474 | 0.84 | LMNA (0.33) | LMNATHRBSMN1; SMN2DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7767624-B2 | 3-Heterocyclyl substituted benzoic acid derivatives | BASF AKTIENGESELLSCHAFT (DE) | 2010-08-03 | — | — | US | disclosed |