⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20887362 | 1.00 | — | — | |
| SCHEMBL31165507 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL2689743 | 0.97 | DRD2 (0.32) | — | |
| Hydrochloric Acid SCHEMBL27800094 | 0.97 | — | — | |
| Bromide SCHEMBL28185084 | 0.97 | — | — | |
| Propane SCHEMBL27604302 | 0.91 | SLC6A2 (0.36) | — | |
| SCHEMBL28119690 | 0.89 | — | — | |
| Carbamic Acid SCHEMBL27853526 | 0.87 | SLC6A2 (0.37) | — | |
| SCHEMBL21585766 | 0.84 | — | — | |
| Morpholine SCHEMBL27773894 | 0.82 | MEN1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1092 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4140989-B1 | 2-ARYLTHIAZOLE DERIVATIVE OR SALT THEREOF, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | HEXAPHARMATEC CO LTD (KR) | 2024-07-17 | — | — | EP | claimed |
| CN-116283916-B | Compound with Axl and c-Met kinase inhibition activity and preparation and application thereof | 中国科学院上海药物研究所 | 2024-06-11 | — | — | CN | claimed |
| CN-115667233-B | Novel 2-arylthiazole derivative or salt thereof, process for preparing the same and pharmaceutical composition comprising the same | 六合医药科技有限公司 | 2024-05-24 | — | — | CN | claimed |
| CN-117924339-A | Hydrogen sulfide donor and preparation method and application thereof | 重庆理工大学 | 2024-04-26 | — | — | CN | claimed |
| CN-116813827-A | Amino-terminated morpholine derivative modified anhydride dispersing agent and preparation method thereof | 无锡颐景丰科技有限公司 | 2023-09-29 | — | — | CN | claimed |
| US-20230219908-A1 | NOVEL 2-ARYLTHIAZOLE DERIVATIVE OR SALT THEREOF, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | HEXAPHARMATEC CO., LTD. (KR) | 2023-07-13 | — | — | US | claimed |
| CN-116102605-A | Dehalogenation method of 9-halogenated steroid compound | 奥锐特药业股份有限公司 | 2023-05-12 | — | — | CN | claimed |
| CN-113200809-B | Device and process for separating n-butane-isobutane-butene through partition wall extractive distillation | 烟台大学 | 2023-03-21 | — | — | CN | claimed |
| EP-4140989-A1 | NOVEL 2-ARYLTHIAZOLE DERIVATIVE OR SALT THEREOF, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | Hexapharmatec Co., Ltd. (KR) | 2023-03-01 | — | — | EP | claimed |
| CN-114057666-B | Synthesis method of 4, 5-disubstituted-2-aminothiazole compound | 沈阳药科大学 | 2023-02-07 | — | — | CN | claimed |
| WO-1992020643-A1 | NOVEL BI-AROMATIC COMPOUNDS DERIVED FROM A SALICILIC PATTERN, METHOD OF PREPARATION AND USE IN HUMAN AND VETERINARY MEDECINE AND IN COSMETICS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (CIRD GALDERMA) (FR) | 1992-11-26 | — | — | WO | claimed |
| CN-1041364-A | Imidazo [2,1-b] quinazolines-5 (the 3H)-ketone and relevant tricyclic compound that replace | MERRELL DOW PHARMA (US) | 1990-04-18 | — | — | CN | claimed |
| EP-0001914-B1 | ANTIBACTERIALLY ACTIVE AMIDES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID AMIDES | BEECHAM GROUP PLC (GB) | 1981-05-20 | — | — | EP | claimed |
| US-4219626-A | Accelerators for radical polymerization reactions with initiators free from peroxide groups | BAYER AKTIENGESELLSCHAFT (DE) | 1980-08-26 | — | — | US | claimed |
| US-4200635-A | MONIC ACID A AMIDES | BEECHAM GROUP LIMITED (GB) | 1980-04-29 | — | — | US | claimed |
| US-4170703-A | 5-Hydroxy-PGI1 morpholinylamides | THE UPJOHN COMPANY (US) | 1979-10-09 | — | — | US | claimed |
| EP-0001914-A2 | Antibacterially active amides, process for their preparation and pharmaceutical compositions containing said amides | BEECHAM GROUP PLC (GB) | 1979-05-16 | — | — | EP | claimed |
| US-4137403-A | 9-Deoxy-9-methylene-PGF2 cycloamides | THE UPJOHN COMPANY (US) | 1979-01-30 | — | — | US | claimed |
| US-4128712-A | 9-Deoxy-9-methylene-PGF1 -morpholinylamides | THE UPJOHN COMPANY (US) | 1978-12-05 | — | — | US | claimed |
| US-3976593-A | TRIETHANOLAMINE BISULFITE, CORROSION INHIBITOR | PETROLITE CORPORATION (US) | 1976-08-24 | — | — | US | claimed |