Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.43 |
| ▸ | RELA | Q04206 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13205218 | 0.85 | LMNA (0.48) | NPC1SMN1; SMN2LMNANFKB1NFKB2 | |
| SCHEMBL13610322 | 0.85 | LMNA (0.47) | NPC1SMN1; SMN2LMNANFKB1NFKB2 | |
| SCHEMBL13205229 | 0.83 | NPC1 (0.51) | NPC1SMN1; SMN2LMNANFKB1NFKB2 | |
| SCHEMBL13610331 | 0.82 | LMNA (0.46) | NPC1SMN1; SMN2LMNANFKB1NFKB2 | |
| SCHEMBL8709685 | 0.81 | NPC1 (0.60) | NPC1SMN1; SMN2LMNANFKB1NFKB2 | |
| SCHEMBL11296728 | 0.81 | NPC1 (0.60) | NPC1SMN1; SMN2LMNANFKB1NFKB2 | |
| SCHEMBL11298386 | 0.81 | NPC1 (0.60) | NPC1SMN1; SMN2LMNANFKB1NFKB2 | |
| SCHEMBL8451854 | 0.81 | NPC1 (0.60) | NPC1SMN1; SMN2LMNANFKB1NFKB2 | |
| SCHEMBL11293806 | 0.81 | NPC1 (0.60) | NPC1SMN1; SMN2LMNANFKB1NFKB2 | |
| SCHEMBL11298650 | 0.81 | NPC1 (0.60) | NPC1SMN1; SMN2LMNANFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7780870-B2 | Liquid crystal composition, liquid crystal element, and siloxane polymer | FUJIFILM CORPORATION (JP) | 2010-08-24 | — | — | US | disclosed |
| US-20080152843-A1 | Liquid Crystal Composition, Liquid Crystal Element, and Siloxane Polymer | FUJIFILM CORPORATION (JP) | 2008-06-26 | — | — | US | disclosed |