SCHEMBL13206252 — predicted protein targets

Predicted protein targets (top 13)

	gene	UniProt	supporting neighbours	confidence
▸	PTPN11	Q06124	5/20	0.53

▸	ACLY	P53396	5/20	0.50

▸	PTPN1	P18031	2/20	0.48

▸	AKR1C3	P42330	1/20	0.47

▸	AKR1C2	P52895	1/20	0.47

▸	AKR1C1	Q04828	1/20	0.47

▸	PTPN6	P29350	1/20	0.47

▸	PLK1	P53350	2/20	0.46

▸	TP53	P04637	1/20	0.46

▸	MAPK8	P45983	1/20	0.43

▸	PPARD	Q03181	2/20	0.43

▸	PPARA	Q07869	1/20	0.43

▸	WDR5	P61964	1/20	0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL12121495	0.91	PTPN11 (0.51)	PTPN11ACLYPTPN1AKR1C3AKR1C2
SCHEMBL12165967	0.90	PTPN11 (0.53)	PTPN11ACLYPTPN1AKR1C3AKR1C2
SCHEMBL12121601	0.89	LRRK2 (0.51)	PTPN11ACLYPTPN1PTPN6
SCHEMBL12121536	0.87	PTPN11 (0.50)	PTPN11ACLYPTPN1AKR1C3AKR1C2
SCHEMBL12166056	0.87	PTPN11 (0.50)	PTPN11ACLYPTPN1AKR1C3AKR1C2
SCHEMBL12121604	0.86	ACLY (0.54)	PTPN11ACLYPTPN1AKR1C3AKR1C2
SCHEMBL12166024	0.86	PTPN11 (0.49)	PTPN11ACLYPTPN1AKR1C3AKR1C2
SCHEMBL12121607	0.86	PTPN11 (0.49)	PTPN11ACLYPTPN1AKR1C3AKR1C2
SCHEMBL12166000	0.85	PTPN11 (0.48)	PTPN11ACLYPTPN1AKR1C3AKR1C2
SCHEMBL13206300	0.85	PTPN11 (0.48)	PTPN11ACLYPTPN1AKR1C3AKR1C2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2010087430-A1	N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF	富山化学工業株式会社 (JP)	2010-08-05	—	—	WO	disclosed