Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 2/20 | 0.67 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.67 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.61 |
| ▸ | CA12 | O43570 | 3/20 | 0.57 |
| ▸ | CA4 | P22748 | 3/20 | 0.57 |
| ▸ | CA7 | P43166 | 3/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | TYR | P14679 | 2/20 | 0.57 |
| ▸ | DPP4 | P27487 | 2/20 | 0.56 |
| ▸ | MMP2 | P08253 | 1/20 | 0.54 |
| ▸ | MMP3 | P08254 | 1/20 | 0.54 |
| ▸ | MMP9 | P14780 | 1/20 | 0.54 |
| ▸ | MMP12 | P39900 | 1/20 | 0.54 |
| ▸ | MMP13 | P45452 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27729071 | 1.00 | PRKCA (0.67) | PRKCACYP19A1AKR1B1CA12CA4 | |
| SCHEMBL29456792 | 1.00 | PRKCA (0.67) | PRKCACYP19A1AKR1B1CA12CA4 | |
| SCHEMBL30214379 | 1.00 | PRKCA (0.67) | PRKCACYP19A1AKR1B1CA12CA4 | |
| SCHEMBL29509697 | 0.88 | PRKCA (0.65) | PRKCACYP19A1AKR1B1CA12CA4 | |
| SCHEMBL27728972 | 0.88 | PRKCA (0.54) | PRKCACYP19A1AKR1B1CA12CA4 | |
| SCHEMBL30384071 | 0.86 | AKR1B1 (0.78) | PRKCACYP19A1AKR1B1CA12CA4 | |
| SCHEMBL30383254 | 0.86 | AKR1B1 (0.78) | PRKCACYP19A1AKR1B1CA12CA4 | |
| SCHEMBL28901133 | 0.85 | PRKCA (0.72) | PRKCACYP19A1AKR1B1CA12CA4 | |
| SCHEMBL28035112 | 0.84 | PRKCA (0.75) | PRKCACYP19A1AKR1B1CYP3A4DPP4 | |
| SCHEMBL28390903 | 0.83 | PRKCA (0.68) | PRKCACYP19A1AKR1B1CYP3A4DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7780997-B2 | Pharmaceutically active extracts of vitex leucoxylon, a process of extracting the same and a method of treating diabetes and inflammatory diseases therewith | LAILA IMPEX (IN) | 2010-08-24 | — | — | US | disclosed |