Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 5/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | GRM8 | O00222 | 1/20 | 0.33 |
| ▸ | GRM6 | O15303 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.33 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.32 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3465515 | 1.00 | GABRR1 (0.36) | GABRR1SLC1A2GRM2CYP2C9CYP2C19 | |
| SCHEMBL3464490 | 1.00 | GABRR1 (0.36) | GABRR1SLC1A2GRM2CYP2C9CYP2C19 | |
| SCHEMBL2296098 | 1.00 | GABRR1 (0.36) | GABRR1SLC1A2GRM2CYP2C9CYP2C19 | |
| SCHEMBL950906 | 1.00 | GABRR1 (0.36) | GABRR1SLC1A2GRM2CYP2C9CYP2C19 | |
| SCHEMBL3464832 | 1.00 | GABRR1 (0.36) | GABRR1SLC1A2GRM2CYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL949715 | 0.98 | GABRR1 (0.34) | GABRR1SLC1A2GRM2CYP2C9CYP2C19 | |
| SCHEMBL949713 | 0.83 | — | — | |
| SCHEMBL13795027 | 0.83 | — | — | |
| SCHEMBL17662660 | 0.81 | — | — | |
| SCHEMBL10958962 | 0.78 | KDM4E (0.43) | LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8822720-B2 | Method for the organocatalytic activation of carboxylic acids for chemical, reactions using orthosubstituted arylboronic acids | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2014-09-02 | — | — | US | disclosed |
| US-8822720-B2 | Method for the organocatalytic activation of carboxylic acids for chemical, reactions using orthosubstituted arylboronic acids | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2014-09-02 | — | — | US | disclosed |
| US-20100197960-A1 | METHOD FOR THE ORGANOCATALYTIC ACTIVATION OF CARBOXYLIC ACIDS FOR CHEMICAL, REACTIONS USING ORTHOSUBSTITUTED ARYLBORONIC ACIDS | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2010-08-05 | — | — | US | disclosed |
| US-20100197960-A1 | METHOD FOR THE ORGANOCATALYTIC ACTIVATION OF CARBOXYLIC ACIDS FOR CHEMICAL, REACTIONS USING ORTHOSUBSTITUTED ARYLBORONIC ACIDS | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2010-08-05 | — | — | US | disclosed |
| WO-2009030022-A1 | METHOD FOR THE ORGANOCATALYTIC ACTIVATION OF CARBOXYLIC ACIDS FOR CHEMICAL REACTIONS USING ORTHOSUBSTITUTED ARYLBORONIC ACIDS | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2009-03-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197960-A1 | METHOD FOR THE ORGANOCATALYTIC ACTIVATION OF CARBOXYLIC ACIDS FOR CHEMICAL, REACTIONS USING ORTHOSUBSTITUTED ARYLBORONIC ACIDS | AOC2, AOC3, OXER1 | GABRR1 1255/4885SLC1A2 790/4885GRM2 576/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.