Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | METAP1 | P53582 | 2/20 | 0.36 |
| ▸ | BPTF | Q12830 | 1/20 | 0.36 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 2/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2915785 | 0.81 | ADORA2A (0.42) | SMN1; SMN2MAPTMAPK1RAB9AKMT2A | |
| SCHEMBL2918205 | 0.80 | CYP2C9 (0.41) | SMN1; SMN2MAPTMAPK1RAB9AKMT2A | |
| SCHEMBL13213234 | 0.78 | ADORA2A (0.38) | — | |
| SCHEMBL2916868 | 0.78 | ABL1 (0.35) | CNR2GAALMNAKMT2A | |
| SCHEMBL2921476 | 0.77 | CFTR (0.45) | L3MBTL1 | |
| SCHEMBL2914146 | 0.77 | RPA1 (0.45) | MAPTTSHR | |
| SCHEMBL13855348 | 0.77 | ALDH1A1 (0.39) | GAADCTPP1LMNATSHRKMT2A | |
| SCHEMBL5265554 | 0.77 | SYK (0.38) | CNR2GAADCTPP1LMNAKMT2A | |
| SCHEMBL2914740 | 0.76 | GRM5 (0.40) | GAADCTPP1LMNATSHRKMT2A | |
| SCHEMBL5270200 | 0.76 | ABL1 (0.35) | GAALMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1591443-B1 | PYRAZOLE DERIVATIVE | DAIICHI SANKYO CO LTD (JP) | 2010-08-25 | — | — | EP | disclosed |