Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 18/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 8/20 | 0.36 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13117539 | 0.86 | CD274 (0.49) | CD274PDCD1PDCD1LG2S1PR1S1PR3 | |
| SCHEMBL13213662 | 0.82 | CD274 (0.35) | CD274PDCD1 | |
| SCHEMBL13117560 | 0.78 | ALDH1A1 (0.36) | CD274PDCD1PDCD1LG2DGAT1 | |
| SCHEMBL13117734 | 0.77 | CD274 (0.42) | CD274PDCD1 | |
| SCHEMBL13117624 | 0.75 | CD274 (0.40) | CD274PDCD1S1PR1S1PR3 | |
| SCHEMBL13970686 | 0.74 | CD274 (0.40) | CD274PDCD1S1PR1S1PR3 | |
| SCHEMBL13117541 | 0.74 | CD274 (0.40) | CD274PDCD1S1PR1S1PR3 | |
| SCHEMBL9964446 | 0.74 | CD274 (0.40) | CD274PDCD1DGAT1S1PR1S1PR3 | |
| SCHEMBL13117538 | 0.74 | CD274 (0.40) | CD274PDCD1S1PR1S1PR3 | |
| SCHEMBL13213358 | 0.72 | ALDH1A1 (0.35) | CD274PDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2216330-A1 | OXADIAZOLIDINEDIONE COMPOUND | Astellas Pharma Inc. (JP) | 2010-08-11 | — | — | EP | disclosed |