Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 14/20 | 0.43 |
| ▸ | GPR6 | P46095 | 1/20 | 0.37 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.36 |
| ▸ | DCK | P27707 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3020792 | 0.90 | SCD (0.54) | SCDSCD5 | |
| SCHEMBL3025483 | 0.79 | SCD (0.42) | SCDSCD5 | |
| SCHEMBL2764141 | 0.78 | SCD (0.49) | SCDSCD5 | |
| SCHEMBL13213664 | 0.74 | SCD (0.50) | SCD | |
| SCHEMBL3009182 | 0.74 | SCD (0.74) | SCDSCD5 | |
| SCHEMBL2783336 | 0.67 | SCD (0.40) | SCDSCD5 | |
| SCHEMBL4682397 | 0.67 | EPHX2 (0.46) | SCD | |
| SCHEMBL2764334 | 0.67 | SCD (0.57) | SCDSCD5 | |
| SCHEMBL12402220 | 0.66 | NPC1 (0.42) | GPR6 | |
| SCHEMBL3336610 | 0.66 | SCD (0.59) | SCDSCD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100197692-A1 | BICYCLIC HETEROAROMATIC COMPOUNDS AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE | MERCK FROSST CANADA LTD. | 2010-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197692-A1 | BICYCLIC HETEROAROMATIC COMPOUNDS AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE | SCD, SCD5, CPT1A | SCD 1/4885GPR6 1825/4885SCD5 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.