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Sugi Predict / Targets / SCD5

SCD5

Stearoyl-CoA desaturase 5 · Q86SK9 · SCD5 on Sugi Atlas →

18,541 patent compounds predicted against SCD5, 7,792 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL949773 SCHEMBL949773 0.50 14/20
SCHEMBL949477 SCHEMBL949477 0.52 13/20
SCHEMBL1166907 SCHEMBL1166907 0.46 12/20
SCHEMBL951879 SCHEMBL951879 0.53 10/20
SCHEMBL950486 SCHEMBL950486 0.49 9/20
SCHEMBL1594529 SCHEMBL1594529 0.47 9/20
SCHEMBL1167565 SCHEMBL1167565 0.46 9/20
SCHEMBL1809091 SCHEMBL1809091 0.85 8/20
SCHEMBL1810127 SCHEMBL1810127 0.61 8/20
SCHEMBL1475692 SCHEMBL1475692 0.58 8/20
SCHEMBL1167745 SCHEMBL1167745 0.50 8/20
SCHEMBL1167232 SCHEMBL1167232 0.49 8/20
SCHEMBL1166583 SCHEMBL1166583 0.46 8/20
SCHEMBL1546554 SCHEMBL1546554 0.43 8/20
SCHEMBL256556 SCHEMBL256556 0.50 7/20
SCHEMBL1166600 SCHEMBL1166600 0.48 7/20
SCHEMBL1166245 SCHEMBL1166245 0.44 7/20
SCHEMBL1166674 SCHEMBL1166674 0.43 7/20
SCHEMBL1166335 SCHEMBL1166335 0.42 7/20
SCHEMBL1546111 SCHEMBL1546111 0.42 7/20

Clinical trials — most relevant to SCD5 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Exploratory Study of the Effects of Omega-3-acid Ethyl Esters on the Lipid and Lipoprotein Profile in the Blood PHASE4COMPLETED
Effects of Docosahexaenoic Acid (DHA) on Heart Rate Variability in Elderly Patients PHASE2/PHASE3COMPLETED
Obesity and Asthma: Nutrigenetic Response to Omega-3 Fatty Acids PHASE2/PHASE3COMPLETED
Effect of Fish-oil on Non-alcoholic Steatohepatitis (NASH) PHASE2COMPLETED
Polyunsaturated Fatty Acids (PUFA) in Diabetic Fatty Liver PHASE2COMPLETED
The Sleep, Liver Evaluation and Effective Pressure Study PHASE2COMPLETED
Pharmacodynamic Effects of a Free-Fatty Acid Formulation of Omega-3 Pentaenoic Acid in Adults With Hypertriglyceridemia PHASE2COMPLETED
Treatment of Bronchial Asthma With Borage and Echium Seed Oils PHASE1/PHASE2COMPLETED
Fish Oil Supplementation, Nutrigenomics and Colorectal Cancer Prevention PHASE2COMPLETED
Vitamin E and DHA-EE on NAFLD - Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Clinical Trial (PUVENAFLD) PHASE2COMPLETED
Liver Positron Emission Tomography (PET) Study of Non Alcoholic Fatty Liver Disease EARLY_PHASE1COMPLETED
Serum FFA Desaturase Activity Index in Patients on High Dose Corticosteroids nanUNKNOWN
Omega-3 vs Very Low Calorie Diet for Liver Size Reduction nanUNKNOWN
EPICO: (Study for the Pro-resolution of Chronic Inflammation in Obesity. Original Acronym From Spanish) nanUNKNOWN
Effect of Dietary SFA and Fructose on Hepatic Insulin Sensitivity nanCOMPLETED
Stearoyl-CoA Desaturase and Energy Metabolism in Humans nanCOMPLETED
Fish Oil and Nonalcoholic Fatty Liver Disease (NAFLD) Study nanCOMPLETED
Activity of Essential Fatty Acid Elongation/Desaturation Pathway During Early Life in Human Infants, In Vivo nanCOMPLETED
Heart & Health Study nanCOMPLETED
Effects of Fish Oils on Inflammation and Insulin Resistance nanCOMPLETED
Liver Fat as a Dietary Target for Treating Cardiometabolic Disorders in Prediabetes and Type 2 Diabetes nanCOMPLETED
Acute Fatty Acid Intervention Study (AFAST) nanCOMPLETED
The Role of Sugars in Fat Accumulation in the Liver nanRECRUITING
Androgens and NAFLD Longitudinal Cohort Study nanRECRUITING
Screening of Healthy Adults for Genetic Variations That Control Fatty Acid Processing nanCOMPLETED
Glucose Metabolism in Sickle Cell Disease nanACTIVE_NOT_RECRUITING
De Novo Lipogenesis in Severity of NAFLD nanCOMPLETED
Metabolic Syndrome and Fatty Liver Disease Among Egyptian Patients with Chronic HBV nanNOT_YET_RECRUITING
Glycemic Index/Saturated Fatty Acid Diet and Hepatic Fat nanCOMPLETED
Omics-based Predictors of NAFLD/Potential NASH nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a SCD5 binder may also engage these)

ProteinNameSimilarity
Q2KIA4 — 1.000 Q2KIA4 →
Q6T707 — 0.999 Q6T707 →
P07308 — 0.997 P07308 →
Q92038 — 0.995 Q92038 →
P13011 — 0.994 P13011 →
P13516 — 0.994 P13516 →
Q6P7B9 — 0.994 Q6P7B9 →
SCD Stearoyl-CoA desaturase 0.994 landscape →
Q99PL7 — 0.994 Q99PL7 →
A0A0C5Q309 — 0.994 A0A0C5Q309 →
Q64420 — 0.992 Q64420 →
O62849 — 0.992 O62849 →
B7SB91 — 0.992 B7SB91 →
Q95MI7 — 0.991 Q95MI7 →
G5ED44 — 0.991 G5ED44 →
O02858 — 0.991 O02858 →
G5EGN2 — 0.991 G5EGN2 →
Q9TT94 — 0.990 Q9TT94 →
Q6US81 — 0.990 Q6US81 →
Q75PL7 — 0.990 Q75PL7 →
O44390 — 0.988 O44390 →
Q8ISS3 — 0.988 Q8ISS3 →
P48623 — 0.987 P48623 →
Q9SP61 — 0.987 Q9SP61 →
Q9BH41 — 0.986 Q9BH41 →
G5EGH6 — 0.986 G5EGH6 →
B7SB92 — 0.985 B7SB92 →
Q3EBF7 — 0.985 Q3EBF7 →
P48618 — 0.985 P48618 →
P32291 — 0.985 P32291 →