Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 2/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 2/20 | 1.00 |
| ▸ | TP53 | P04637 | 2/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 2/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 1.00 |
| ▸ | NPC1 | O15118 | 1/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 1/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 1/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 1/20 | 1.00 |
| ▸ | CHRNA7 | P36544 | 9/20 | 0.97 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.97 |
| ▸ | GMNN | O75496 | 2/20 | 0.97 |
| ▸ | LMNA | P02545 | 2/20 | 0.97 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.97 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.97 |
| ▸ | HPGD | P15428 | 2/20 | 0.97 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.97 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.97 |
| ▸ | CHRNA10 | Q9GZZ6 | 5/20 | 0.59 |
| ▸ | CHRNA9 | Q9UGM1 | 5/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL1320371 | 0.98 | CHRNA7 (1.00) | MTORCYP3A4TP53CYP2D6HSD17B10 | |
| SCHEMBL21925693 | 0.84 | MTOR (0.73) | MTORCYP3A4TP53CYP2D6HSD17B10 | |
| SCHEMBL7534905 | 0.84 | MTOR (0.73) | MTORCYP3A4TP53CYP2D6HSD17B10 | |
| SCHEMBL436231 | 0.74 | RELA (1.00) | MTORCYP3A4TP53CYP2D6HSD17B10 | |
| SCHEMBL5496245 | 0.74 | RELA (1.00) | MTORCYP3A4TP53CYP2D6HSD17B10 | |
| SCHEMBL27659104 | 0.74 | NPC1 (0.58) | MTORCYP3A4TP53CYP2D6HSD17B10 | |
| SCHEMBL17609114 | 0.73 | CHRNA7 (0.63) | MTORCYP3A4TP53CYP2D6HSD17B10 | |
| SCHEMBL17609112 | 0.73 | CHRNA7 (0.63) | MTORCYP3A4TP53CYP2D6HSD17B10 | |
| SCHEMBL19132177 | 0.72 | TP53 (0.56) | MTORCYP3A4TP53CYP2D6HSD17B10 | |
| SCHEMBL5741015 | 0.72 | RELA (0.72) | MTORCYP3A4TP53CYP2D6HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8058243-B2 | Method for treating a brain cancer with ifenprodil | HSC RESEARCH AND DEVELOPMENT LIMITED PARTNERSHIP (CA) | 2011-11-15 | — | — | US | disclosed |