Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13201567 | 0.79 | PDE2A (0.38) | BRD4 | |
| SCHEMBL19476925 | 0.77 | NR1H2 (0.36) | BRD4 | |
| SCHEMBL594548 | 0.73 | BRD4 (0.40) | BRD4 | |
| SCHEMBL400585 | 0.73 | BRD4 (0.30) | BRD4 | |
| SCHEMBL594547 | 0.71 | CCNE1 (0.39) | — | |
| SCHEMBL16790684 | 0.66 | SMN1; SMN2 (0.41) | BRD4 | |
| SCHEMBL13218216 | 0.66 | ALDH1A1 (0.36) | — | |
| SCHEMBL12365544 | 0.66 | BRD4 (0.39) | BRD4 | |
| SCHEMBL18168816 | 0.64 | BRD4 (0.32) | BRD4 | |
| SCHEMBL18742167 | 0.64 | PDE2A (0.40) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1973917-B1 | PROTEIN KINASE INHIBITORS | ABBVIE INC (US) | 2015-06-10 | — | — | EP | disclosed |
| US-7772231-B2 | Substituted pyrazolo[3,4-d]pyrimidines as protein kinase inhibitors | ABBOTT LABORATORIES (US) | 2010-08-10 | — | — | US | disclosed |