Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.59 |
| ▸ | NPC1 | O15118 | 4/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13609827 | 0.86 | MAPT (0.45) | MAPTNPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL14130014 | 0.84 | NPC1 (0.49) | MAPTNPC1HTTRAB9AKMT2A | |
| SCHEMBL14130074 | 0.82 | MEN1 (0.46) | MAPTNPC1HTTRAB9AKMT2A | |
| SCHEMBL30620152 | 0.82 | MAPT (0.63) | MAPTNPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL28287460 | 0.81 | MAPT (0.66) | MAPTNPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL27973104 | 0.81 | MAPT (0.66) | MAPTNPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL14130401 | 0.80 | MEN1 (0.50) | MAPTNPC1HTTRAB9AKMT2A | |
| SCHEMBL11506742 | 0.80 | RXFP1 (0.58) | MAPTNPC1HTTRXFP1KMT2A | |
| SCHEMBL21186448 | 0.79 | MEN1 (0.56) | MAPTNPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL13815343 | 0.76 | MEN1 (0.76) | MAPTNPC1HTTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8491993-B2 | Polymeric dyes, overcoat compositions and thermal lithographic printing plates | AMERICAN DYE SOURCE, INC. (CA) | 2013-07-23 | — | — | US | disclosed |
| US-8491993-B2 | Polymeric dyes, overcoat compositions and thermal lithographic printing plates | AMERICAN DYE SOURCE, INC. (CA) | 2013-07-23 | — | — | US | disclosed |
| EP-2173827-B1 | POLYMERIC DYES, OVERCOAT COMPOSITIONS AND THERMAL LITHOGRAPHIC PRINTING PLATES | AMERICAN DYE SOURCE INC (CA) | 2013-02-13 | — | — | EP | disclosed |
| US-20100215944-A1 | POLYMERIC DYES, OVERCOAT COMPOSITIONS AND THERMAL LITHOGRAPHIC PRINTING PLATES | AMERICAN DYE SOURCE, INC. (CA) | 2010-08-26 | — | — | US | disclosed |
| US-20100215944-A1 | POLYMERIC DYES, OVERCOAT COMPOSITIONS AND THERMAL LITHOGRAPHIC PRINTING PLATES | AMERICAN DYE SOURCE, INC. (CA) | 2010-08-26 | — | — | US | disclosed |
| US-20090035694-A1 | POLYMERIC DYES, OVERCOAT COMPOSITIONS AND THERMAL LITHOGRAPHIC PRINTING PLATES | AMERICAN DYE SOURCE, INC. (CA) | 2009-02-05 | — | — | US | disclosed |
| WO-2009015467-A1 | POLYMERIC DYES, OVERCOAT COMPOSITIONS AND THERMAL LITHOGRAPHIC PRINTING PLATES | AMERICAN DYE SOURCE INC. (CA) | 2009-02-05 | — | — | WO | disclosed |
| US-20090035694-A1 | POLYMERIC DYES, OVERCOAT COMPOSITIONS AND THERMAL LITHOGRAPHIC PRINTING PLATES | AMERICAN DYE SOURCE, INC. (CA) | 2009-02-05 | — | — | US | disclosed |