Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.66 |
| ▸ | NPC1 | O15118 | 5/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | RAB9A | P51151 | 5/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27973104 | 1.00 | MAPT (0.66) | MAPTNPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL4000024 | 0.84 | CHRM1 (0.50) | MAPTNPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL14621405 | 0.81 | HPGD (0.49) | MAPTNPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL30620152 | 0.81 | MAPT (0.63) | MAPTNPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL13219022 | 0.81 | MAPT (0.59) | MAPTNPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL5183351 | 0.79 | TGM2 (0.50) | MAPTNPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL30532455 | 0.79 | NPC1 (0.56) | MAPTNPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL29074600 | 0.79 | NPC1 (0.56) | MAPTNPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL28836945 | 0.78 | MAPT (0.53) | MAPTNPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL38651149 | 0.78 | ALDH1A1 (0.57) | MAPTNPC1HTTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109574871-B | Acetaminoazobenzene derivative and preparation and application thereof | 上海交通大学 | 2022-01-04 | — | — | CN | claimed |
| CN-109574871-A | A kind of acetylamino azobenzene derivative and its preparation and application | 上海交通大学 | 2019-04-05 | — | — | CN | claimed |
| CN-109574871-B | Acetaminoazobenzene derivative and preparation and application thereof | 上海交通大学 | 2022-01-04 | — | — | CN | disclosed |
| CN-109574871-B | Acetaminoazobenzene derivative and preparation and application thereof | 上海交通大学 | 2022-01-04 | — | — | CN | disclosed |
| CN-109574871-A | A kind of acetylamino azobenzene derivative and its preparation and application | 上海交通大学 | 2019-04-05 | — | — | CN | disclosed |
| CN-109574871-A | A kind of acetylamino azobenzene derivative and its preparation and application | 上海交通大学 | 2019-04-05 | — | — | CN | disclosed |
| CN-109574871-A | A kind of acetylamino azobenzene derivative and its preparation and application | 上海交通大学 | 2019-04-05 | — | — | CN | disclosed |