Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 13/20 | 0.84 |
| ▸ | TNF | P01375 | 7/20 | 0.75 |
| ▸ | PARP1 | P09874 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13200167 | 0.92 | ADAM17 (0.80) | ADAM17TNFPARP1 | |
| SCHEMBL13200178 | 0.92 | ADAM17 (0.81) | ADAM17TNF | |
| SCHEMBL13200163 | 0.92 | ADAM17 (0.81) | ADAM17TNF | |
| SCHEMBL13200912 | 0.92 | ADAM17 (1.00) | ADAM17TNFPARP1 | |
| SCHEMBL13201116 | 0.91 | ADAM17 (0.91) | ADAM17TNFPARP1 | |
| SCHEMBL13825321 | 0.90 | ADAM17 (0.89) | ADAM17TNFPARP1 | |
| SCHEMBL13201102 | 0.89 | ADAM17 (0.88) | ADAM17TNFPARP1 | |
| SCHEMBL13201241 | 0.89 | ADAM17 (0.77) | ADAM17TNFPARP1 | |
| SCHEMBL13200320 | 0.88 | ADAM17 (0.83) | ADAM17TNF | |
| SCHEMBL8237439 | 0.88 | ADAM17 (1.00) | ADAM17TNFPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7772263-B2 | Compounds for the treatment of inflammatory disorders | SCHERING CORPORATION (US) | 2010-08-10 | — | — | US | disclosed |