Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15325087 | 0.77 | SMN1; SMN2 (0.31) | SMN1; SMN2 | |
| SCHEMBL3886801 | 0.75 | NCF1 (0.41) | SMN1; SMN2 | |
| SCHEMBL17779823 | 0.75 | SMN1; SMN2 (0.30) | SMN1; SMN2 | |
| SCHEMBL13116870 | 0.75 | SMN1; SMN2 (0.54) | SMN1; SMN2 | |
| SCHEMBL467970 | 0.74 | — | — | |
| SCHEMBL12482322 | 0.73 | CHRM1 (0.39) | — | |
| SCHEMBL13534637 | 0.73 | SMN1; SMN2 (0.31) | SMN1; SMN2 | |
| SCHEMBL3123800 | 0.70 | ATM (0.34) | SMN1; SMN2 | |
| SCHEMBL975740 | 0.70 | CA12 (0.41) | SMN1; SMN2 | |
| SCHEMBL1127536 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7786143-B2 | Thiazolyl piperidine derivatives | HOFFMAN-LA ROCHE INC. (US) | 2010-08-31 | — | — | US | disclosed |