Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALB | P02768 | 5/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GLP1R | P43220 | 8/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | CASP2 | P42575 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14118084 | 0.95 | FOLH1 (0.46) | ALBFOLH1NOD1GLP1RCASP2 | |
| SCHEMBL31688586 | 0.91 | FOLH1 (0.51) | ALBFOLH1NOD1TSHRGLP1R | |
| SCHEMBL13223698 | 0.89 | ALB (0.48) | ALBFOLH1NOD1TSHRGLP1R | |
| SCHEMBL14118034 | 0.89 | FOLH1 (0.51) | ALBFOLH1NOD1GLP1RCASP2 | |
| SCHEMBL20900398 | 0.86 | EPHX2 (0.51) | ALBFOLH1NOD1GLP1REPHX2 | |
| SCHEMBL20900403 | 0.86 | EPHX2 (0.51) | ALBFOLH1NOD1GLP1REPHX2 | |
| SCHEMBL25357657 | 0.86 | NAAA (0.53) | ALBFOLH1NOD1GLP1RCASP2 | |
| SCHEMBL25357653 | 0.86 | NAAA (0.53) | ALBFOLH1NOD1GLP1RCASP2 | |
| SCHEMBL25358482 | 0.86 | FOLH1 (0.52) | ALBFOLH1NOD1GLP1REPHX2 | |
| SCHEMBL25358474 | 0.86 | FOLH1 (0.52) | ALBFOLH1NOD1GLP1REPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8454936-B2 | Metal chelators and methods of their use | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2013-06-04 | — | — | US | disclosed |
| US-7785565-B2 | Metal chelators and methods of their use | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2010-08-31 | — | — | US | disclosed |
| US-20100189645-A1 | METAL CHELATORS AND METHODS OF THEIR USE | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HOMELAND A (US) | 2010-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100189645-A1 | METAL CHELATORS AND METHODS OF THEIR USE | SLC30A5, SLC30A7, SLC30A6 | ALB 580/4885FOLH1 15/4885NOD1 3445/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.