SCHEMBL132285

SCHEMBL132285

c1cc2nccc-2[nH]n1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL19459238 0.98 LTA4H (0.47)
SCHEMBL19459028 0.91 JMJD6 (0.45)
Boric Acid SCHEMBL28276648 0.91 JMJD6 (0.45)
SCHEMBL29487831 0.86 KDM4E (0.56)
SCHEMBL1703342 0.86 KDM4E (0.56)
SCHEMBL28890975 0.84 KDM4E (0.54)
SCHEMBL31164805 0.84 KDM4E (0.54)
SCHEMBL15500845 0.82 PDPK1 (0.52)
SCHEMBL11983702 0.79 CCR1 (0.59)
SCHEMBL16877067 0.79 GSK3B (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1226 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025082069-A1 COMPOUND BINDING TO CRBN PROTEIN AND DEGRADATION AGENT OF PROTEIN 中国海洋大学 2025-04-24 WO claimed
WO-2025085347-A1 IL4I1 INHIBITORS AND USES THEREOF MERCK SHARP & DOHME LLC (US) 2025-04-24 WO claimed
CN-119841843-A Compound combined with CRBN protein and degradation agent of CRBN protein 中国海洋大学 2025-04-18 CN claimed
US-20240246959-A1 BENZIMIDAZOLE DERIVATIVE AND PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF SHENZHEN SALUBRIS PHARMACEUTICALS CO., LTD. (CN) 2024-07-25 US claimed
WO-2024027755-A1 PROTAC CHIMERIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF 杭州中美华东制药有限公司 2024-02-08 WO claimed
CN-117466884-A Heterocyclic compounds or salts thereof as ATR kinase inhibitors, pharmaceutical compositions containing same and uses thereof 德州大学系统董事会 2024-01-30 CN claimed
CN-112218631-B Heterocyclic inhibitors of ATR kinase 德州大学系统董事会 2023-12-22 CN claimed
CN-116848119-A Pyrrolopyridazine compound, and preparation method and application thereof 杭州中美华东制药有限公司 2023-10-03 CN claimed
EP-4242202-A1 BENZIMIDAZOLE DERIVATIVE AND PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF Shenzhen Salubris Pharmaceuticals Co., Ltd. (CN) 2023-09-13 EP claimed
CN-116410940-A Asymmetric reduction method for potential chiral carbon-carbon double bond by using alkene reductase and mutant thereof 上海合全药业股份有限公司 2023-07-11 CN claimed
EP-1254907-A1 PYRROLOPYRIDAZINE COMPOUND Sankyo Company, Limited (JP) 2002-11-06 EP claimed
US-20020156079-A1 Optically active pyrrolopyridazine derivatives SANKYO COMPANY, LIMITED (JP) 2002-10-24 US claimed
CN-1370172-A Optically active pyrrolopyridazine compound SANKYO CO (JP) 2002-09-18 CN claimed
US-20020086920-A1 METHOD FOR IMPROVING ADHENSION OF WATER-BASED INKS TO HALOGEN- CONTAINING RESIN ARTICLES PMC CINCINNATI, INC. 2002-07-04 US claimed
EP-1186607-A1 OPTICALLY ACTIVE PYRROLOPYRIDAZINE COMPOUNDS Sankyo Company, Limited (JP) 2002-03-13 EP claimed
EP-1055704-A2 Method for improving adhesion of water based inks to halogen containing resin articles ROHM AND HAAS COMPANY (US) 2000-11-29 EP claimed
US-6063782-A Pyrrolopyridazine derivatives SANKYO COMPANY, LIMITED (JP) 2000-05-16 US claimed
CN-1044811-C Pyrrolopyridazine derivatives SANKYO CO (JP) 1999-08-25 CN claimed
CN-1143964-A Pyrrolopyridazine derivative SANKYO CO (JP) 1997-02-26 CN claimed
EP-0742218-A1 PYRROLOPYRIDAZINE DERIVATIVE SANKYO COMPANY LIMITED (JP) 1996-11-13 EP claimed