Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 3/20 | 0.51 |
| ▸ | CNR1 | P21554 | 4/20 | 0.45 |
| ▸ | RHOA | P61586 | 3/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | RHOC | P08134 | 2/20 | 0.35 |
| ▸ | ACLY | P53396 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8260726 | 1.00 | STS (0.51) | STSCNR1RHOAHDAC3HDAC4 | |
| SCHEMBL13698765 | 0.86 | STS (0.47) | STSCNR1RHOAHDAC3HDAC4 | |
| SCHEMBL2921990 | 0.85 | STS (0.70) | STSCNR1 | |
| SCHEMBL8260230 | 0.81 | STS (0.49) | STSCNR1RHOAHCRTR1HCRTR2 | |
| SCHEMBL13175781 | 0.80 | STS (0.43) | STSCNR1EPHX2AKR1C3L3MBTL1 | |
| SCHEMBL5605623 | 0.76 | STS (0.60) | STSCNR1RHOARHOC | |
| SCHEMBL13363856 | 0.71 | STS (0.51) | STSCNR1ACLYKDR | |
| SCHEMBL2925179 | 0.70 | STS (0.62) | STSCNR1RHOAEPHX2RHOC | |
| SCHEMBL2952898 | 0.67 | STS (1.00) | STSEPHX2 | |
| SCHEMBL3936688 | 0.65 | ACP1 (0.45) | STSCNR1HDAC8L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100204146-A1 | Treatment of Oestrogen Dependant Conditions in Pre-menopausal Women | PREGLEM S.A. (CH) | 2010-08-12 | — | — | US | disclosed |
| US-20100204146-A1 | Treatment of Oestrogen Dependant Conditions in Pre-menopausal Women | PREGLEM S.A. (CH) | 2010-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100204146-A1 | Treatment of Oestrogen Dependant Conditions in Pre-menopausal Women | STS, CYP19A1, SHBG | STS 1/4885CNR1 2761/4885RHOA 4241/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.