Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL467402 | 0.94 | SIGMAR1 (1.00) | SIGMAR1KCNH2 | |
| Oxalic Acid SCHEMBL19691742 | 0.92 | SIGMAR1 (0.94) | SIGMAR1KCNH2 | |
| SCHEMBL5184983 | 0.92 | SIGMAR1 (0.94) | SIGMAR1KCNH2 | |
| Oxalic Acid SCHEMBL1896696 | 0.92 | SIGMAR1 (0.94) | SIGMAR1KCNH2 | |
| SCHEMBL467254 | 0.85 | SIGMAR1 (0.84) | SIGMAR1KCNH2 | |
| SCHEMBL467255 | 0.85 | SIGMAR1 (0.82) | SIGMAR1KCNH2 | |
| Oxalic Acid SCHEMBL19691744 | 0.83 | SIGMAR1 (0.79) | SIGMAR1KCNH2 | |
| Oxalic Acid SCHEMBL1897462 | 0.83 | SIGMAR1 (0.79) | SIGMAR1KCNH2 | |
| Oxalic Acid SCHEMBL19692414 | 0.82 | SIGMAR1 (0.78) | SIGMAR1KCNH2 | |
| Oxalic Acid SCHEMBL1897458 | 0.82 | SIGMAR1 (0.78) | SIGMAR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8314096-B2 | Sigma receptor inhibitors | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2012-11-20 | — | — | US | disclosed |
| US-8314096-B2 | Sigma receptor inhibitors | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2012-11-20 | — | — | US | disclosed |
| US-20100190781-A1 | SIGMA RECEPTOR INHIBITORS | ESTEVE PHARMACEUTICALS, S.A. (ES) | 2010-07-29 | — | — | US | disclosed |
| US-20100190781-A1 | SIGMA RECEPTOR INHIBITORS | ESTEVE PHARMACEUTICALS, S.A. (ES) | 2010-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100190781-A1 | SIGMA RECEPTOR INHIBITORS | SIGMAR1, TMEM97, OPRL1 | SIGMAR1 1/4885KCNH2 1365/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.