Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.76 |
| ▸ | CA12 | O43570 | 4/20 | 0.72 |
| ▸ | CA2 | P00918 | 4/20 | 0.72 |
| ▸ | CA9 | Q16790 | 4/20 | 0.72 |
| ▸ | CA1 | P00915 | 3/20 | 0.72 |
| ▸ | GAA | P10253 | 3/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.70 |
| ▸ | LMNA | P02545 | 3/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.66 |
| ▸ | HTR1A | P08908 | 2/20 | 0.66 |
| ▸ | HTR1D | P28221 | 2/20 | 0.66 |
| ▸ | HTR1B | P28222 | 2/20 | 0.66 |
| ▸ | NAMPT | P43490 | 1/20 | 0.66 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2948364 | 0.91 | CA12 (0.79) | MAPTCA12CA2CA9CA1 | |
| SCHEMBL13234933 | 0.91 | MAPT (0.76) | MAPTCA12CA2CA9CA1 | |
| SCHEMBL13234942 | 0.87 | MAPT (0.79) | MAPTCA12CA2CA9CA1 | |
| SCHEMBL13234932 | 0.86 | MAPT (1.00) | MAPTCA12CA2CA9CA1 | |
| SCHEMBL13234947 | 0.86 | MAPT (1.00) | MAPTCA12CA2CA9CA1 | |
| SCHEMBL13234938 | 0.82 | CA12 (0.77) | MAPTCA12CA2CA9CA1 | |
| SCHEMBL13234968 | 0.82 | CA12 (0.66) | MAPTCA12CA2CA9CA1 | |
| SCHEMBL13234915 | 0.81 | MAPT (0.77) | MAPTCA12CA2CA9CA1 | |
| SCHEMBL13234944 | 0.80 | CA12 (0.89) | MAPTCA12CA2CA9CA1 | |
| SCHEMBL27646179 | 0.80 | CACNA1G (0.54) | MAPTCA12CA2CA9CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100173917-A1 | UREA DERIVATIVES AS ABL MODULATORS | AMBIT BIOSCIENCES CORPORATION | 2010-07-08 | — | — | US | disclosed |
| US-20100173917-A1 | UREA DERIVATIVES AS ABL MODULATORS | AMBIT BIOSCIENCES CORPORATION | 2010-07-08 | — | — | US | disclosed |
| US-7750160-B2 | Isoxazolyl urea derivatives as kinase modulators | AMBIT BIOSCIENCES CORPORATION (US) | 2010-07-06 | — | — | US | disclosed |
| US-7750160-B2 | Isoxazolyl urea derivatives as kinase modulators | AMBIT BIOSCIENCES CORPORATION (US) | 2010-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100173917-A1 | UREA DERIVATIVES AS ABL MODULATORS | ABL1, ABL2, BCR | MAPT 1165/4885CA12 4593/4885CA2 3207/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.