Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALB | P02768 | 3/20 | 0.60 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.46 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.45 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.43 |
| ▸ | GNPAT | O15228 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | GLP1R | P43220 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13057101 | 0.92 | FOLH1 (0.55) | ALBFOLH1NOD1GNPATGLP1R | |
| SCHEMBL23451113 | 0.87 | FOLH1 (0.63) | ALBFOLH1SMN1; SMN2NOD1SIRT6 | |
| SCHEMBL13286041 | 0.87 | ALB (0.62) | ALBFOLH1SMN1; SMN2NOD1SIRT6 | |
| SCHEMBL21078712 | 0.85 | NOD1 (0.56) | ALBFOLH1NOD1GNPATGLP1R | |
| SCHEMBL21078710 | 0.85 | NOD1 (0.56) | ALBFOLH1NOD1GNPATGLP1R | |
| SCHEMBL19069648 | 0.84 | ALB (0.56) | ALBFOLH1SMN1; SMN2NOD1SIRT6 | |
| SCHEMBL15871316 | 0.84 | ALB (0.56) | ALBFOLH1SMN1; SMN2NOD1SIRT6 | |
| SCHEMBL25542879 | 0.84 | NOD1 (0.65) | ALBFOLH1NOD1SIRT6SIRT1 | |
| SCHEMBL2735591 | 0.84 | FOLH1 (0.71) | ALBFOLH1SMN1; SMN2SIRT6SIRT1 | |
| SCHEMBL16393150 | 0.84 | FOLH1 (0.71) | ALBFOLH1SMN1; SMN2SIRT6SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7759357-B2 | Phenylpyrimidine amines as IgE inhibitors | NOVARTIS AG (CH) | 2010-07-20 | — | — | US | disclosed |
| US-20070281956-A1 | Phenylpyrimidine amines as IgE inhibitors | NOVARTIS AG (CH) | 2007-12-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070281956-A1 | Phenylpyrimidine amines as IgE inhibitors | FCER2, SELP, FCGR2A | ALB 366/4885FOLH1 1314/4885SMN1; SMN2 4789/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.