⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6934656 | 0.83 | TSHR (0.50) | — | |
| SCHEMBL4745526 | 0.83 | TSHR (0.50) | — | |
| SCHEMBL1003894 | 0.83 | TSHR (0.50) | — | |
| SCHEMBL54330 | 0.79 | — | — | |
| SCHEMBL15445 | 0.79 | — | — | |
| SCHEMBL17626634 | 0.79 | TSHR (0.53) | — | |
| Bromide SCHEMBL28271631 | 0.76 | — | — | |
| Iodide SCHEMBL28289332 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL2784721 | 0.76 | — | — | |
| Bromide SCHEMBL6657855 | 0.76 | TSHR (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3377565-A1 | POLYMERIC SUBSTRATE WITH A SURFACE HAVING REDUCED BIOMOLECULE ADHESION, AND THERMOPLASTIC ARTICLES OF SUCH SUBSTRATE | SiO2 Medical Products, Inc. (US) | 2018-09-26 | — | — | EP | disclosed |
| US-20180149977-A1 | COMPOSITION FOR COATING RESIST PATTERN | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2018-05-31 | — | — | US | disclosed |
| US-9403932-B2 | Process for producing silica-comprising polyol dispersions and their use for producing polyurethane materials | BASF SE (DE) | 2016-08-02 | — | — | US | disclosed |
| US-20110266497-A1 | PROCESS FOR PRODUCING SILICA-COMPRISING POLYOL DISPERSIONS AND THEIR USE FOR PRODUCING POLYURETHANE MATERIALS | BASF SE (DE) | 2011-11-03 | — | — | US | disclosed |