Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | ADH1B | P00325 | 3/20 | 0.44 |
| ▸ | ADH1A | P07327 | 3/20 | 0.44 |
| ▸ | ADH7 | P40394 | 3/20 | 0.44 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6934656 | 1.00 | TSHR (0.50) | TSHRALDH1A1ADH1BADH1AADH7 | |
| SCHEMBL1003894 | 1.00 | TSHR (0.50) | TSHRALDH1A1ADH1BADH1AADH7 | |
| SCHEMBL17626634 | 0.95 | TSHR (0.53) | TSHRALDH1A1ADH1BADH1AADH7 | |
| SCHEMBL15445 | 0.95 | — | — | |
| Bromide SCHEMBL6657855 | 0.92 | TSHR (0.44) | TSHRALDH1A1ADH1BADH1AADH7 | |
| Bromide SCHEMBL3468246 | 0.91 | — | — | |
| SCHEMBL7184374 | 0.91 | — | — | |
| SCHEMBL21176007 | 0.91 | — | — | |
| Propane SCHEMBL20526066 | 0.91 | TSHR (0.50) | TSHRALDH1A1ADH1BADH1AADH7 | |
| SCHEMBL6910828 | 0.91 | TSHR (0.50) | TSHRALDH1A1ADH1BADH1AADH7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3959208-B1 | CYCLEN BASED COMPOUNDS, COORDINATION COMPOUNDS, PEPTIDES, PHARMACEUTICAL PREPARATION, AND USE THEREOF | USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR V V I (CZ) | 2023-07-05 | — | — | EP | disclosed |
| EP-3611169-B1 | NEW GADOLINIUM CHELATE COMPOUNDS FOR USE IN MAGNETIC RESONANCE IMAGING | Bayer Pharma AG (DE) | 2021-07-21 | — | — | EP | disclosed |
| EP-3269395-A1 | AMINOALCOHOL LIPIDOIDS AND USES THEREOF | Massachusetts Institute Of Technology (US) | 2018-01-17 | — | — | EP | disclosed |
| WO-2017144376-A1 | ALKYLENE OXIDE- AND HYDROCARBYL-SUBSTITUTED POLYCARBOXYLIC ACID OF QUATERNIZED NITROGEN COMPOUNDS AS FRICTION-REDUCING ADDITIVE FOR FUELS | BASF SE (DE) | 2017-08-31 | — | — | WO | disclosed |
| US-20170204075-A1 | AMINOALCOHOL LIPIDOIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2017-07-20 | — | — | US | disclosed |
| US-20170128572-A1 | LONG-LIVED GADOLINIUM BASED TUMOR TARGETED IMAGING AND THERAPY AGENTS | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2017-05-11 | — | — | US | disclosed |
| US-9556110-B2 | Aminoalcohol lipidoids and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2017-01-31 | — | — | US | disclosed |
| EP-2691772-B1 | LIGAND FUNCTIONAL SUBSTRATES | 3M INNOVATIVE PROPERTIES CO (US) | 2016-06-08 | — | — | EP | disclosed |
| US-20160152662-A1 | LIGAND FUNCTIONAL SUBSTRATES | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY | 2016-06-02 | — | — | US | disclosed |
| US-9272246-B2 | Ligand functional substrates | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2016-03-01 | — | — | US | disclosed |
| US-20100331234-A1 | AMINOALCOHOL LIPIDOIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2010-12-30 | — | — | US | disclosed |
| WO-2008130721-A1 | PREPARATION OF SECONDARY DIAMINES | ALBEMARLE CORPORATION (US) | 2008-10-30 | — | — | WO | disclosed |
| WO-2008112636-A1 | CHAIN EXTENDERS | ALBEMARLE CORPORATION (US) | 2008-09-18 | — | — | WO | disclosed |
| US-5914072-A | DISPERSANTS FOR SOLIDS; FOR USE IN PAINTS, INKS | BASF AKTIENGESELLSCHAFT (DE) | 1999-06-22 | — | — | US | disclosed |
| US-5863879-A | POLYMER IS FORMED BY REACTING A POLYMER CONTAINING VINYLAMINE UNIT WITH COMPOUNDS CONTAINING ALDEHYDE OR KETO GROUPS AND OPTIONAL OTHER AMINE OR ALOCHOL CONTAINING COMPOUNDS SUCH AS AMINAL, HEMIAMINAL OR AMINAL ACETATE | BASF AKTIENGESELLSCHAFT (DE) | 1999-01-26 | — | — | US | disclosed |
| EP-0756618-B1 | DYE-TRANSFER INHIBITORS FOR DETERGENTS | BASF AG (DE) | 1998-08-12 | — | — | EP | disclosed |
| EP-0759440-A2 | Phosphoric acid esters | BASF AKTIENGESELLSCHAFT (DE) | 1997-02-26 | — | — | EP | disclosed |
| EP-0756618-A1 | DYE-TRANSFER INHIBITORS FOR DETERGENTS | BASF AKTIENGESELLSCHAFT (DE) | 1997-02-05 | — | — | EP | disclosed |
| WO-1995029221-A1 | DYE-TRANSFER INHIBITORS FOR DETERGENTS | BASF AKTIENGESELLSCHAFT (DE) | 1995-11-02 | — | — | WO | disclosed |
| US-4179469-A | Preparation of amines | UOP INC. (US) | 1979-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170128572-A1 | LONG-LIVED GADOLINIUM BASED TUMOR TARGETED IMAGING AND THERAPY AGENTS | H1-3, H1-2, H1-4 | TSHR 609/4885ALDH1A1 3398/4885ADH1B 3215/4885 |
| US-20160152662-A1 | LIGAND FUNCTIONAL SUBSTRATES | PCNA, POLM, POLL | TSHR 4365/4885ALDH1A1 4565/4885ADH1B 4833/4885 |
| US-20170204075-A1 | AMINOALCOHOL LIPIDOIDS AND USES THEREOF | PHOSPHO1, PNMT, AASDHPPT | TSHR 4458/4885ALDH1A1 568/4885ADH1B 578/4885 |
| US-20100331234-A1 | AMINOALCOHOL LIPIDOIDS AND USES THEREOF | PHOSPHO1, PNMT, AASDHPPT | TSHR 4458/4885ALDH1A1 568/4885ADH1B 578/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.