Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13382574 | 0.84 | MAPT (0.43) | MAPT | |
| SCHEMBL23022360 | 0.82 | MAPT (0.55) | MAPTIDO1TDO2 | |
| SCHEMBL13265094 | 0.82 | MAPT (0.55) | MAPTIDO1TDO2 | |
| SCHEMBL14472687 | 0.81 | MAPT (0.61) | MAPTIDO1TDO2 | |
| SCHEMBL14495396 | 0.80 | MAPT (0.68) | MAPTIDO1TDO2TSHRHIF1A | |
| SCHEMBL14495406 | 0.80 | MAPT (0.68) | MAPTIDO1TDO2TSHRHIF1A | |
| SCHEMBL22140862 | 0.79 | MAPT (0.75) | MAPTTSHRHIF1AGMNNLMNA | |
| SCHEMBL22984176 | 0.79 | MAPT (0.75) | MAPTTSHRHIF1AGMNNLMNA | |
| SCHEMBL22107925 | 0.77 | MAPT (0.57) | MAPTIDO1TDO2 | |
| SCHEMBL14181277 | 0.77 | MAPT (0.57) | MAPTIDO1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9180111-B2 | Reduction in complement activation and inflammation during tissue injury by carotenoids, carotenoid analogs, or derivatives thereof | CARDAX PHARMA, INC. (US) | 2015-11-10 | — | — | US | disclosed |
| US-7763649-B2 | Carotenoid analogs or derivatives for controlling connexin 43 expression | CARDAX PHARMACEUTICALS, INC. (US) | 2010-07-27 | — | — | US | disclosed |
| US-7723327-B2 | Carotenoid ester analogs or derivatives for the inhibition and amelioration of liver disease | CARDAX PHARMACEUTICALS, INC. (US) | 2010-05-25 | — | — | US | disclosed |
| US-7691901-B2 | Carotenoid analogs or derivatives for the inhibition and amelioration of inflammation | CARDAX PHARMACEUTICALS INC. (US) | 2010-04-06 | — | — | US | disclosed |
| US-7691901-B2 | Carotenoid analogs or derivatives for the inhibition and amelioration of inflammation | CARDAX PHARMACEUTICALS INC. (US) | 2010-04-06 | — | — | US | disclosed |
| US-7592449-B2 | Structural carotenoid analogs for the inhibition and amelioration of disease | CARDAX PHARMACEUTICALS, INC. (US) | 2009-09-22 | — | — | US | disclosed |
| US-7592449-B2 | Structural carotenoid analogs for the inhibition and amelioration of disease | CARDAX PHARMACEUTICALS, INC. (US) | 2009-09-22 | — | — | US | disclosed |
| US-7521584-B2 | Carotenoid analogs or derivatives for the inhibition and amelioration of disease | CARDAX PHARMACEUTICALS, INC. (US) | 2009-04-21 | — | — | US | disclosed |
| US-7521584-B2 | Carotenoid analogs or derivatives for the inhibition and amelioration of disease | CARDAX PHARMACEUTICALS, INC. (US) | 2009-04-21 | — | — | US | disclosed |
| US-7375133-B2 | Pharmaceutical compositions including carotenoid ether analogs or derivatives for the inhibition and amelioration of disease | CARDAX PHARMACEUTICALS, INC. (US) | 2008-05-20 | — | — | US | disclosed |
| US-7345091-B2 | Carotenoid ether analogs or derivatives for the inhibition and amelioration of disease | CARDAX PHARMACEUTICALS, INC. (US) | 2008-03-18 | — | — | US | disclosed |
| US-7320997-B2 | Pharmaceutical compositions including carotenoid ester analogs or derivatives for the inhibition and amelioration of disease | CARDAX PHARMACEUTICALS, INC. (US) | 2008-01-22 | — | — | US | disclosed |
| US-7317008-B2 | Carotenoid ester analogs or derivatives for the inhibition and amelioration of ischemic reperfusion injury | CARDAX PHARMACEUTICALS, INC. (US) | 2008-01-08 | — | — | US | disclosed |
| US-7317008-B2 | Carotenoid ester analogs or derivatives for the inhibition and amelioration of ischemic reperfusion injury | CARDAX PHARMACEUTICALS, INC. (US) | 2008-01-08 | — | — | US | disclosed |