Quindoxin

Quindoxin

SCHEMBL1323909

[O-][n+]1cc[n+]([O-])c2ccccc21

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.43
LMNA P02545 1/20 0.42
HTT P42858 1/20 0.42
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
POLB P06746 1/20 0.37
CASP6 P55212 1/20 0.37
BCHE P06276 8/20 0.32
ACHE P22303 8/20 0.32
KDM4E B2RXH2 2/20 0.31
TDP1 Q9NUW8 1/20 0.31
MITF O75030 1/20 0.31
MAPT P10636 1/20 0.31
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Quindoxin SCHEMBL29462546 1.00 ATM (0.43) ATMLMNAHTTMEN1KMT2A
SCHEMBL7900240 0.87 HTT (0.42) ATMLMNAHTTMEN1KMT2A
SCHEMBL9531 0.77 ATM (0.48) ATMBCHEACHE
SCHEMBL27684621 0.75 ATM (0.46) ATMBCHEACHE
Fluoride SCHEMBL27608168 0.75 ATM (0.46) ATMBCHEACHE
SCHEMBL28126562 0.75 ATM (0.46) ATMBCHEACHE
Hydrochloric Acid SCHEMBL7370284 0.75 BCHE (0.50) BCHEACHE
Water SCHEMBL5786021 0.75 ATM (0.46) ATMBCHEACHE
SCHEMBL29627789 0.72 ATM (0.63) ATMLMNAHTTMEN1KMT2A
SCHEMBL6919829 0.72 ATM (0.63) ATMLMNAHTTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 426 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114621195-A quinoxaline-N1,N4-dioxide derivatives 华中农业大学 2022-06-14 CN claimed
CN-110269859-B Application of quinoxaline-1, 4-dioxide compound in resisting toxoplasma gondii infection 中国农业科学院上海兽医研究所(中国动物卫生与流行病学中心上海分中心) 2022-05-17 CN claimed
CN-106727576-B Use of quinoxaline-1, 4-dioxide derivatives as potentiators of colistin sulphate 广州英赛特生物技术有限公司 2020-08-04 CN claimed
CN-106727576-A Quinoxaline -1,4- dioxide derivatives as colistine sulfate synergist application 广州英赛特生物技术有限公司 2017-05-31 CN claimed
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
WO-2013006854-A2 COMPOSITIONS AND METHODS FOR TREATING ENTEROBACTERIACEAE INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2013-01-10 WO claimed
US-7968713-B2 Method of synthesizing quinoxaline derivative by microwave irradiation NIHON UNIVERSITY (JP) 2011-06-28 US claimed
CN-101914071-A Preparation method of 2-methyquinoxaline-1,4-dioxide UNIV CHINA AGRICULTURAL 2010-12-15 CN claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US claimed
CN-101182313-B Chemical synthesis technique of quinoxaline LANZHOU VETERINARY RES INST CHINESE ACADEMY OF AGRICULTURE SCEENCES 2010-08-18 CN claimed
EP-0101582-A1 Light-stabilized quinoxaline-di-N oxides BAYER AG (DE) 1984-02-29 EP claimed
US-4373101-A BACTERICIDES; ANIMAL GROWTH REGULATORS; LOW TOXICITY; ANIMAL HUSBANDRY EGYT GYOGYSZERVEGYESZETI GYAR (HU) 1983-02-08 US claimed
US-4348389-A Quinoxaline adducts useful as anthelmintics INTERNATIONAL MINERALS & CHEMICAL CORP. (US) 1982-09-07 US claimed
WO-1982001001-A1 2-HYDROXYMETHYL-QUINOXALINE-1,4-DIOXIDE DERIVATIVES,A PROCESS FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAME MATRAI E 1982-04-01 WO claimed
US-4254120-A VETINARY MEDICINES CIBA-GEIGY CORPORATION (US) 1981-03-03 US claimed
US-4224324-A CONTROLLING GROWTH OF BACTERIA AND FUNGI INTERNATIONAL MINERALS AND CHEMICAL CORPORATION (US) 1980-09-23 US claimed
US-4211781-A Process for the preparation of dustless quinoxaline-1,4-dioxide animal feed supplement premixes PFIZER INC. (US) 1980-07-08 US claimed
EP-0001618-A2 Process for the preparation of di-N-oxides and their pharmaceutical use BAYER AG (DE) 1979-05-02 EP claimed
US-4092415-A ANIMAL GROWTH REGULATORS CIBA-GEIGY CORPORATION (US) 1978-05-30 US claimed
US-4091206-A ANIMAL GROWTH REGULATORS EGYT GYOGYSZERVEGYESZETI GYAR (HU) 1978-05-23 US claimed