Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 6/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 6/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.46 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.46 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.45 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.39 |
| ▸ | TYMS | P04818 | 1/20 | 0.39 |
| ▸ | OTC | P00480 | 1/20 | 0.38 |
| ▸ | GLUL | P15104 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21568887 | 0.84 | LPAR3 (0.61) | S1PR2S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL13239603 | 0.82 | S1PR2 (0.50) | S1PR2S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL14210023 | 0.82 | TYMS (0.58) | S1PR2S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL14029178 | 0.79 | KDM4E (0.54) | S1PR2S1PR1S1PR3S1PR4BTN3A1 | |
| SCHEMBL2953046 | 0.78 | LPAR3 (0.67) | S1PR2S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL6688615 | 0.78 | LPAR3 (0.67) | S1PR2S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL13239617 | 0.78 | MEN1 (0.57) | S1PR2S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL2948337 | 0.77 | LPAR3 (0.64) | S1PR2S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL13239611 | 0.76 | BTN3A1 (0.42) | LPAR3LPAR2BTN3A1TYMSOTC | |
| SCHEMBL388416 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7754200-B2 | Phosphate transport inhibitors | GENZYME CORPORATION (US) | 2010-07-13 | — | — | US | disclosed |