Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 7/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 7/20 | 0.50 |
| ▸ | S1PR3 | Q99500 | 7/20 | 0.50 |
| ▸ | S1PR4 | O95977 | 6/20 | 0.50 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.50 |
| ▸ | SAT1 | P21673 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.41 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.41 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL767556 | 0.84 | S1PR2 (0.68) | S1PR2S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL767878 | 0.84 | S1PR2 (0.68) | S1PR2S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL766904 | 0.84 | S1PR2 (0.68) | S1PR2S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL767663 | 0.84 | S1PR2 (0.68) | S1PR2S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL13239581 | 0.82 | S1PR2 (0.46) | S1PR2S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL6688615 | 0.78 | LPAR3 (0.67) | S1PR2S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL2953046 | 0.78 | LPAR3 (0.67) | S1PR2S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL13239617 | 0.77 | MEN1 (0.57) | S1PR2S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL2948337 | 0.76 | LPAR3 (0.64) | S1PR2S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL14029178 | 0.74 | KDM4E (0.54) | S1PR2S1PR1S1PR3S1PR4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7754200-B2 | Phosphate transport inhibitors | GENZYME CORPORATION (US) | 2010-07-13 | — | — | US | disclosed |