Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.79 |
| ▸ | TSHR | P16473 | 1/20 | 0.79 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PTP4A1 | Q93096 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27647336 | 0.89 | ALDH1A1 (1.00) | ALDH1A1TSHRCYP2C9MAPTKDM4E | |
| SCHEMBL29445 | 0.89 | — | — | |
| SCHEMBL20706534 | 0.86 | ALDH1A1 (0.79) | ALDH1A1TSHRCYP2C9MAPTKDM4E | |
| Acetonitrile SCHEMBL23070461 | 0.85 | ALDH1A1 (0.92) | ALDH1A1TSHRCYP2C9MAPTKDM4E | |
| SCHEMBL4826914 | 0.84 | ALDH1A1 (0.75) | ALDH1A1TSHRCYP2C9MAPTKDM4E | |
| Acetic Acid SCHEMBL8429279 | 0.83 | ALDH1A1 (0.88) | ALDH1A1TSHRCYP2C9MAPTKDM4E | |
| SCHEMBL2412075 | 0.83 | ALDH1A1 (0.88) | ALDH1A1TSHRCYP2C9MAPTKDM4E | |
| SCHEMBL9346940 | 0.81 | ALDH1A1 (0.85) | ALDH1A1TSHRCYP2C9MAPTKDM4E | |
| Butadiene SCHEMBL10811584 | 0.81 | ALDH1A1 (0.85) | ALDH1A1TSHRCYP2C9MAPTKDM4E | |
| Acrylonitrile SCHEMBL10893622 | 0.80 | ALDH1A1 (0.81) | ALDH1A1TSHRCYP2C9MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10196471-B1 | Curable composition having an electron deficient olefin | Henkel IP & Holding GmbH (DE) | 2019-02-05 | — | — | US | disclosed |
| EP-2217559-B1 | ELECTRON DEFICIENT OLEFINS | Henkel IP & Holding GmbH (DE) | 2017-06-28 | — | — | EP | disclosed |
| US-9481640-B2 | Electron deficient olefins | Henkel IP & Holding GmbH (DE) | 2016-11-01 | — | — | US | disclosed |
| US-20150191424-A1 | ELECTRON DEFICIENT OLEFINS | Henkel IP & Holding GmbH (DE) | 2015-07-09 | — | — | US | disclosed |
| US-20100210788-A1 | ELECTRON DEFICIENT OLEFINS | LOCTITE (R&D) LIMITED (IE) | 2010-08-19 | — | — | US | disclosed |
| WO-2009053484-A2 | ELECTRON DEFICIENT OLEFINS AND CURABLE COMPOSITIONS PREPARED THEREFROM | LOCTITE (R & D) LIMITED (IE) | 2009-04-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100210788-A1 | ELECTRON DEFICIENT OLEFINS | MAL2, IDH2, SLC25A11 | ALDH1A1 838/4885TSHR 4873/4885CYP2C9 3047/4885 |
| US-20150191424-A1 | ELECTRON DEFICIENT OLEFINS | MAL2, IDH2, SLC25A11 | ALDH1A1 838/4885TSHR 4873/4885CYP2C9 3047/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.