SCHEMBL1324

SCHEMBL1324

O=C(c1ncc[nH]1)c1ncc[nH]1

nearest known ligand 0.62

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.62
RAB9A P51151 2/20 0.62
KMT2A Q03164 1/20 0.58
SMN1; SMN2 Q16637 2/20 0.45
HTT P42858 1/20 0.45
GLA P06280 1/20 0.42
BRAF P15056 1/20 0.42
HDAC1 Q13547 1/20 0.42
F2RL1 P55085 1/20 0.41
ALDH1A1 P00352 3/20 0.40
KDM4E B2RXH2 2/20 0.39
TBXAS1 P24557 2/20 0.37
CSNK1A1 P48729 1/20 0.36
TYRO3 Q06418 1/20 0.36
DYRK1B Q9Y463 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL3543004 0.97 NPC1 (0.60) NPC1RAB9AKMT2ASMN1; SMN2HTT
SCHEMBL10952701 0.97 NPC1 (0.60) NPC1RAB9AKMT2ASMN1; SMN2HTT
Hydrogen Sulfide SCHEMBL28438010 0.97 NPC1 (0.60) NPC1RAB9AKMT2ASMN1; SMN2HTT
Bromide SCHEMBL7371333 0.97 NPC1 (0.60) NPC1RAB9AKMT2ASMN1; SMN2HTT
Ammonia Solution, Strong SCHEMBL16266978 0.97 NPC1 (0.60) NPC1RAB9AKMT2ASMN1; SMN2HTT
SCHEMBL28449908 0.97 NPC1 (0.60) NPC1RAB9AKMT2ASMN1; SMN2HTT
Boric Acid SCHEMBL29132408 0.93 NPC1 (0.56) NPC1RAB9AKMT2ASMN1; SMN2HTT
SCHEMBL27168894 0.93 NPC1 (0.56) NPC1RAB9AKMT2ASMN1; SMN2HTT
Acetone SCHEMBL27732294 0.93 NPC1 (0.61) NPC1RAB9AKMT2ASMN1; SMN2HTT
Sulfurous Acid SCHEMBL31013483 0.91 NPC1 (0.55) NPC1RAB9AKMT2ASMN1; SMN2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 73876 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4746923-A2 DELIVERY SYSTEM COMPRISING LIPID OR POLYMERIC NANOPARTICLES COMPRISING THYROID HORMONES FONDAZIONE RICCARDO TERZI E SILVIO ALBINI (IT) 2026-05-27 EP claimed
CN-122075719-A Neuraminidase-ROS dual-response nano-carrier as well as preparation method and application thereof 2026-05-26 CN claimed
CN-122079954-A Synthesis method of benzo [1,3] oxathia-2-one 2026-05-26 CN claimed
CN-119800543-B Preparation process of antibacterial acrylic fabric Jiangsu Yimolecular Textile Co.,Ltd. (CN) 2026-05-26 CN claimed
CN-122079809-A Synthesis method of dipeptide linker of antibody coupling degradation agent 2026-05-26 CN claimed
CN-122080119-A Synthesis method of MC-Gly-Gly-Phe-Gly tetrapeptide linker 2026-05-26 CN claimed
US-12637702-B2 Process for preparing substituted imidazo[1,5-α]pyrazines HOFFMANN-LA ROCHE INC. (US) 2026-05-26 US claimed
CN-118420550-B N-hydroxyamide compound containing dihydroquinazolinone, and preparation method and application thereof 亳州学院 2026-05-22 CN claimed
US-20260139001-A1 EVOLUTION OF FLUOROGENIC SENSORS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2026-05-21 US claimed
CN-122031612-A Dendrobium huoshanense compound traditional Chinese medicine composition for treating dysmenorrhea and preparation method thereof 安徽神农泽中医药科技发展有限公司 2026-05-15 CN claimed
EP-0017152-A1 Novel heterocyclic substituted pyrazinoylguanidines, processes for preparing and a pharmaceutical composition containing the same MERCK & CO. INC. (US) 1980-10-15 EP claimed
US-4228152-A BOUND TO A POLYACRYLIC OR POLYMETHACRYLIC BACKBONE THROUGH ESTER OR AMIDIC BONDS FERRUTI PAOLO 1980-10-14 US claimed
EP-0010418-A1 Antisecretory guanidine derivatives, processes for their manufacture and pharmaceutical compositions containing them IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1980-04-30 EP claimed
US-4192799-A RADIOIMMUNOASSAY THE UPJOHN COMPANY (US) 1980-03-11 US claimed
US-4189583-A FROM 1-METHYL-2-OXO-3-METHYLENE-4-(3'-METHOXYPHENYL)-4 -(CARBOXYMETHYLENE)PIPERIDINE BY CYCLIZATION THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH, EDUCATION AND WELFARE (US) 1980-02-19 US claimed
EP-0006931-A1 NEW SUBSTITUTED BY-PRODUCTS OF 1,3-DIHYDRO IMIDAZO (4,5-b) PYRIDIN-2-ONE, PROCESS, APPLICATION, COMPOSITIONS AND INTERMEDIATE COMPOUNDS OBTAINED ROUSSEL-UCLAF (FR) 1980-01-23 EP claimed
WO-1979000206-A1 NEW SUBSTITUTED BY-PRODUCTS OF 1,3-DIHYDRO IMIDAZO(4,5-B)PYRIDIN-2-ONE,PROCESS,APPLICATION,COMPOSITIONS AND INTERMEDIATE COMPOUNDS OBTAINED ROUSSEL UCLAF (FR) 1979-04-19 WO claimed
US-4145320-A BOUND TO POLY-ACRYLIC OR METHACRYLIC UNITS THROUGH OXYALKYLENIC, AMINOALKYLENIC, OR OXYAMINOALKYLENIC CHAINS FERRUTI PAOLO 1979-03-20 US claimed
US-4028315-A Solid phase synthesis of peptides E. R. SQUIBB & SONS, INC. (US) 1977-06-07 US claimed
US-4002598-A TENSILE, FLEXURAL STRENGTH TEXACO DEVELOPMENT CORPORATION (US) 1977-01-11 US claimed