Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | BRAF | P15056 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.34 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.33 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.33 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1324 | 0.93 | NPC1 (0.62) | NPC1RAB9AKMT2ASMN1; SMN2HTT | |
| Ammonia Solution, Strong SCHEMBL16266978 | 0.91 | NPC1 (0.60) | NPC1RAB9AKMT2ASMN1; SMN2HTT | |
| Hydrochloric Acid SCHEMBL3543004 | 0.91 | NPC1 (0.60) | NPC1RAB9AKMT2ASMN1; SMN2HTT | |
| SCHEMBL28449908 | 0.91 | NPC1 (0.60) | NPC1RAB9AKMT2ASMN1; SMN2HTT | |
| Hydrogen Sulfide SCHEMBL28438010 | 0.91 | NPC1 (0.60) | NPC1RAB9AKMT2ASMN1; SMN2HTT | |
| SCHEMBL10952701 | 0.91 | NPC1 (0.60) | NPC1RAB9AKMT2ASMN1; SMN2HTT | |
| Bromide SCHEMBL7371333 | 0.91 | NPC1 (0.60) | NPC1RAB9AKMT2ASMN1; SMN2HTT | |
| SCHEMBL27168894 | 0.86 | NPC1 (0.56) | NPC1RAB9AKMT2ASMN1; SMN2HTT | |
| Acetone SCHEMBL27732294 | 0.86 | NPC1 (0.61) | NPC1RAB9AKMT2ASMN1; SMN2HTT | |
| Sulfurous Acid SCHEMBL31013483 | 0.84 | NPC1 (0.55) | NPC1RAB9AKMT2ASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117279924-A | Chemically-ligatable nuclear targeting tags | 西格马-奥尔德里奇有限责任公司 | 2023-12-22 | — | — | CN | disclosed |