SCHEMBL13242011

SCHEMBL13242011

Cc1ccc(C)c(N(C=C(c2ccccc2)c2ccccc2)c2ccc(-c3ccc(N(C=C(c4ccccc4)c4ccccc4)c4cc(C)ccc4C)cc3)cc2)c1

nearest known ligand 0.34

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.34
POLB P06746 2/20 0.34
CTDSP1 Q9GZU7 1/20 0.34
EPHX1 P07099 1/20 0.33
ALDH1A1 P00352 1/20 0.32
GAA P10253 1/20 0.32
ALOX12 P18054 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
KDM4E B2RXH2 1/20 0.30
CES2 O00748 2/20 0.30
CES1 P23141 2/20 0.30
HTT P42858 1/20 0.30
PTGS2 P35354 1/20 0.30
HSD17B1 P14061 1/20 0.30
HSD17B2 P37059 1/20 0.30
PTGES O14684 1/20 0.30
ALOX5 P09917 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5036465 0.89 MAPT (0.34) MAPTPOLBCTDSP1EPHX1ALDH1A1
SCHEMBL13242017 0.89 MAPT (0.34) MAPTPOLBCTDSP1EPHX1ALDH1A1
SCHEMBL4376815 0.88 MAPT (0.36) MAPTPOLBCTDSP1EPHX1ALDH1A1
SCHEMBL25071486 0.86 MAPT (0.35) MAPTPOLBCTDSP1EPHX1ALDH1A1
SCHEMBL16922632 0.86 MAPT (0.33) MAPTPOLBCTDSP1EPHX1ALDH1A1
SCHEMBL24301561 0.85 CES2 (0.33) MAPTPOLBCTDSP1EPHX1ALDH1A1
SCHEMBL17735845 0.84 CES2 (0.40) MAPTPOLBALDH1A1SMN1; SMN2NPSR1
SCHEMBL13242004 0.84 CES2 (0.40) MAPTPOLBALDH1A1SMN1; SMN2NPSR1
SCHEMBL13242019 0.84 CES2 (0.40) MAPTPOLBALDH1A1SMN1; SMN2NPSR1
SCHEMBL13242015 0.83 CES2 (0.33) MAPTALDH1A1NPSR1KDM4ECES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11287756-B2 Positive charging electrophotographic photoreceptor, electrophotographic cartridge and image forming apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2022-03-29 US disclosed
US-8481238-B2 Electrophotographic photoreceptors, electrophotographic photoreceptor cartridge, and image-forming apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2013-07-09 US disclosed
US-8481238-B2 Electrophotographic photoreceptors, electrophotographic photoreceptor cartridge, and image-forming apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2013-07-09 US disclosed
US-20100183332-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTORS, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, AND IMAGE-FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2010-07-22 US disclosed
US-20100183332-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTORS, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, AND IMAGE-FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2010-07-22 US disclosed