Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 16/20 | 1.00 |
| ▸ | CA1 | P00915 | 13/20 | 1.00 |
| ▸ | CA12 | O43570 | 9/20 | 1.00 |
| ▸ | CA9 | Q16790 | 12/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | CA7 | P43166 | 7/20 | 0.54 |
| ▸ | CA5A | P35218 | 5/20 | 0.54 |
| ▸ | CA5B | Q9Y2D0 | 5/20 | 0.54 |
| ▸ | CA6 | P23280 | 2/20 | 0.54 |
| ▸ | CA3 | P07451 | 1/20 | 0.54 |
| ▸ | CA4 | P22748 | 3/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | AGO2 | Q9UKV8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL330045 | 0.84 | CA2 (0.78) | CA2CA1CA12CA9MEN1 | |
| SCHEMBL7570116 | 0.80 | CA2 (0.67) | CA2CA1CA12CA9MEN1 | |
| SCHEMBL29283437 | 0.80 | CA2 (0.67) | CA2CA1CA12CA9MEN1 | |
| SCHEMBL8492321 | 0.78 | CA2 (0.70) | CA2CA1CA12CA9MEN1 | |
| SCHEMBL25033772 | 0.78 | CA2 (0.64) | CA2CA1CA12CA9MEN1 | |
| SCHEMBL202948 | 0.77 | CA2 (0.81) | CA2CA1CA12CA9CA7 | |
| SCHEMBL28417720 | 0.77 | CA2 (0.62) | CA2CA1CA12CA9MEN1 | |
| SCHEMBL9138555 | 0.75 | CA2 (0.60) | CA2CA1CA12CA9NPC1 | |
| P-Toluenesulfonamide SCHEMBL11327034 | 0.74 | CA2 (0.86) | CA2CA1CA12CA9CA7 | |
| SCHEMBL28612608 | 0.74 | CA2 (0.59) | CA2CA1CA12CA9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025215303-A1 | SULFONAMIDES, COMPOSITIONS COMPRISING SAID SULFONAMIDES, METHODS FOR THE PREPARATION OF SAID SULFONAMIDES, AND SAID SULFONAMIDES FOR USE AS MEDICAMENT AND IN A METHOD FOR THE TREATMENT OR PREVENTION OF AN OCULAR DISEASE OR CONDITION, OR IDIOPATHIC INTRACRANIAL HYPERTENSION | ITÄ-SUOMEN YLIOPISTO (FI) | 2025-10-16 | — | — | WO | disclosed |
| US-7756674-B2 | Methods of calculating differences of binding affinities between congeneric pairs of ligands by way of a displaced solvent functional | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2010-07-13 | — | — | US | disclosed |
| US-20090037136-A1 | Methods of calculating differences of binding affinities between congeneric pairs of ligands by way of a displaced solvent functional | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-02-05 | — | — | US | disclosed |