Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 6/20 | 0.38 |
| ▸ | CCL5 | P13501 | 4/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.37 |
| ▸ | ACKR3 | P25106 | 4/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1604053 | 0.77 | MAPK1 (0.55) | — | |
| SCHEMBL1604038 | 0.76 | HTT (0.52) | CNR1CNR2EGFR | |
| SCHEMBL1604127 | 0.73 | MEN1 (0.49) | KDM4E | |
| SCHEMBL1604243 | 0.72 | MKNK1 (0.55) | EGFR | |
| Hydrochloric Acid SCHEMBL1920865 | 0.72 | MEN1 (0.49) | KDM4E | |
| SCHEMBL1604186 | 0.67 | MBTD1 (0.47) | ACKR3 | |
| SCHEMBL12533526 | 0.64 | GRIN2B (0.32) | PAK1 | |
| SCHEMBL30341013 | 0.64 | SLC6A2 (0.54) | KCNH2 | |
| SCHEMBL19528703 | 0.63 | MC4R (0.64) | KCNH2 | |
| SCHEMBL1604737 | 0.62 | MEN1 (0.50) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1797099-B1 | PIPERIDINYLAMINO-THIENO[2,3-D] PYRIMIDINE COMPOUNDS | EPIX DELAWARE INC (US) | 2010-08-11 | — | — | EP | disclosed |