Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 8/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MGAM | O43451 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.40 |
| ▸ | RELA | Q04206 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12052311 | 0.85 | CNR2 (0.51) | CNR2KDM4EMGAMHDAC8MAPT | |
| SCHEMBL6068282 | 0.74 | CNR2 (0.51) | CNR2KDM4EMGAMHDAC8MAPT | |
| SCHEMBL1343443 | 0.74 | CNR2 (0.78) | CNR2KDM4EMGAMHDAC8MAPT | |
| SCHEMBL28234820 | 0.69 | CNR2 (0.75) | CNR2KDM4EMGAMHDAC8MAPT | |
| SCHEMBL30227014 | 0.69 | CNR2 (0.75) | CNR2KDM4EMGAMHDAC8MAPT | |
| SCHEMBL7832199 | 0.68 | CNR2 (1.00) | CNR2KDM4EMGAMHDAC8MAPT | |
| SCHEMBL30227109 | 0.68 | CNR2 (1.00) | CNR2KDM4EMGAMHDAC8MAPT | |
| SCHEMBL29484748 | 0.67 | MGAM (0.68) | CNR2KDM4EMGAMHDAC8MAPT | |
| SCHEMBL29484746 | 0.67 | MGAM (0.68) | CNR2KDM4EMGAMHDAC8MAPT | |
| SCHEMBL29540332 | 0.67 | MGAM (0.68) | CNR2KDM4EMGAMHDAC8MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2394995-B1 | RING-FUSED 2-PYRIDONE DERIVATIVES AND HERBICIDES | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2014-01-15 | — | — | EP | disclosed |
| WO-2010089993-A1 | RING-FUSED 2-PYRIDONE DERIVATIVES AND HERBICIDES | クミアイ化学工業株式会社 (JP) | 2010-08-12 | — | — | WO | disclosed |
| EP-2174934-A1 | OXOPYRAZINE DERIVATIVE AND HERBICIDE | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2010-04-14 | — | — | EP | disclosed |
| EP-1982978-A1 | PYRIDONE DERIVATIVE AND HERBICIDE | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2008-10-22 | — | — | EP | disclosed |