SCHEMBL1324849

SCHEMBL1324849

CC(=O)OCC[SiH](C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1326082 0.85 ALDH1A1 (0.56)
SCHEMBL4950436 0.83 ALDH1A1 (0.52)
SCHEMBL15314023 0.82
SCHEMBL10431008 0.81 ALDH1A1 (0.50)
SCHEMBL18921549 0.81 ALDH1A1 (0.41)
SCHEMBL18921550 0.79
SCHEMBL2685731 0.77
SCHEMBL64593 0.76 ALDH1A1 (0.68)
SCHEMBL961094 0.75 ALDH1A1 (0.44)
SCHEMBL13056203 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102612317-B Aqueous dispersions containing antimicrobials in a hybrid network BASF SE 2015-07-01 CN claimed
CN-102612317-B Aqueous dispersions containing antimicrobials in a hybrid network BASF SE 2015-07-01 CN disclosed
US-8058261-B2 3′-ethynylcytidine derivative TAIHO PHARMACEUTICAL CO., LTD. (JP) 2011-11-15 US disclosed
EP-2045258-B1 3'-ETHYNYLCYTIDINE DERIVATIVE TAIHO PHARMACEUTICAL CO LTD (JP) 2011-09-21 EP disclosed
US-7825103-B2 5'-O-triisopropylsilyl-2'-cyano-2'-deoxy-1- beta -D-arabinofuranosylcytosine; antitumor agents TAIHO PHARMACEUTICAL CO., LTD. (JP) 2010-11-02 US disclosed
US-20090306008-A1 3'-ETHYNYLCYTIDINE DERIVATIVE Sasaki, Takuma (JP) 2009-12-10 US disclosed
US-20090118222-A1 NOVEL PYRIMIDINE NUCLEOSIDE COMPOUND OR ITS SALT TAIHO PHARMACEUTICAL CO., LTD. (JP) 2009-05-07 US disclosed
EP-2045258-A1 3'-ETHYNYLCYTIDINE DERIVATIVE Taiho Pharmaceutical Co., Ltd. (JP) 2009-04-08 EP disclosed
EP-1845102-A1 NOVEL PYRIMIDINE NUCLEOSIDE COMPOUND OR ITS SALT TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) 2007-10-17 EP disclosed
EP-0962481-A2 Sheet and tube siloxane polymers containing a pendent organofunctional group DOW CORNING CORPORATION (US) 1999-12-08 EP disclosed
US-5977248-A POLYSILOXANES DOW CORNING CORPORATION (US) 1999-11-02 US disclosed