SCHEMBL132491

SCHEMBL132491

C[Si](C)(O[Si](C)(C)c1ccc(O)cc1)c1ccc(O)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 8/20 0.50
ESR2 Q92731 6/20 0.50
MEN1 O00255 4/20 0.42
KMT2A Q03164 4/20 0.42
CYP3A4 P08684 4/20 0.42
HSD17B10 Q99714 4/20 0.42
ALOX15 P16050 4/20 0.42
LMNA P02545 3/20 0.42
MAPT P10636 3/20 0.42
CA14 Q9ULX7 3/20 0.42
HIF1A Q16665 3/20 0.42
NPC1 O15118 2/20 0.42
TYR P14679 2/20 0.42
HPGD P15428 2/20 0.42
NFKB1 P19838 2/20 0.42
RAB9A P51151 2/20 0.42
CA12 O43570 2/20 0.42
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
CA9 Q16790 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7520692 0.88 ESR1 (0.45) ESR1ESR2MEN1KMT2ACYP3A4
SCHEMBL7514040 0.88 ESR1 (0.45) ESR1ESR2MEN1KMT2ACYP3A4
SCHEMBL7518293 0.88 ESR1 (0.45) ESR1ESR2MEN1KMT2ACYP3A4
SCHEMBL7514692 0.88 ESR1 (0.45) ESR1ESR2MEN1KMT2ACYP3A4
SCHEMBL7511258 0.88 ESR1 (0.45) ESR1ESR2MEN1KMT2ACYP3A4
SCHEMBL9771063 0.81 ESR1 (0.59) ESR1ESR2MEN1KMT2ACYP3A4
SCHEMBL7649982 0.77 ESR1 (0.45) ESR1ESR2MEN1KMT2ACYP3A4
SCHEMBL9743132 0.76 ACHE (0.44) MEN1KMT2ACYP3A4LMNANPC1
SCHEMBL2299701 0.76 ESR1 (0.31) ESR1ESR2HPGD
SCHEMBL2144488 0.75 ESR1 (0.56) ESR1ESR2MEN1KMT2ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6486293-B1 Electrophotographic photoconductor and method of producing aromatic polycarbonate resin for use in the photoconductor RICOH COMPANY, LTD. (JP) 2002-11-26 US claimed
EP-0220080-B1 COMPOSITIONS BASED ON PHTHALONITRILE-TERMINATED POLYARYLOXY PYRIDINE OLIGOMERS, THEIR PREPARATION, THEIR USE IN THE PREPARATION OF POLYARYLOXY PYRIDINE COPHTHALOCYANINE LATTICES AND LATTICES OBTAINED CENTRE D'ETUDE DES MATERIAUX ORGANIQUES POUR TECHNOLOGIES AVANCEES (FR) 1990-02-07 EP claimed
US-4764578-A Compositions of polyaryloxypyridine oligomers with phthalonitrile end groups, their preparation and use for manufacturing polyaryloxypyridine co-phthalocyanine lattices CENTRE D'ETUDE DES MATERIAUX ORGANIQUES POUR TECHNOLOGIES AVANCEES (FR) 1988-08-16 US claimed
CN-104817581-A Silicon-containing diphenol and preparation method thereof UNIV QUZHOU 2015-08-05 CN disclosed
EP-1542273-B1 Circuit-connecting material and circuit terminal connected structure and connecting method HITACHI CHEMICAL CO LTD (JP) 2013-09-25 EP disclosed
EP-1717851-B1 Circuit-connecting material and circuit terminal connected structure and connecting method HITACHI CHEMICAL CO LTD (JP) 2012-10-17 EP disclosed
US-8142605-B2 Circuit-connecting material and circuit terminal connected structure and connecting method HITACHI CHEMICAL COMPANY, LTD. (JP) 2012-03-27 US disclosed
EP-1521125-B1 Electrophotographic photoconductor, electrophotographic method, electrophotographic apparatus, process cartridge for electrophotographic apparatus and azo compound RICOH CO LTD (JP) 2012-03-07 EP disclosed
US-7967943-B2 Circuit-connecting material and circuit terminal connected structure and connecting method HITACHI CHEMICAL COMPANY, LTD. (JP) 2011-06-28 US disclosed
US-20110114893-A1 CIRCUIT-CONNECTING MATERIAL AND CIRCUIT TERMINAL CONNECTED STRUCTURE AND CONNECTING METHOD HITACHI CHEMICAL CO., LTD. (JP) 2011-05-19 US disclosed
US-7879956-B2 Circuit-connecting material and circuit terminal connected structure and connecting method HITACHI CHEMICAL COMPANY, LTD. (JP) 2011-02-01 US disclosed
US-5976746-A ELECTROCONDUCTIVE SUPPORT; PHOTOCONDUCTIVE LAYER RICOH COMPANY, LTD. (JP) 1999-11-02 US disclosed
US-5942363-A POLYCARBONATE RESIN HAVING TRIARYLAMINE STRUCTURE IN MAIN CHAIN; CHARGE TRANSFER AGENTS RICOH COMPANY, LTD. (JP) 1999-08-24 US disclosed
US-5910561-A A HIGH MOLECULAR WEIGHT CHARGE TRANSPORT HOMOPOLYMER OR COPOLYMER BINDER COMPRISING AN AROMATIC DIHYDROXY WITH A TERTIARY AMINE MONOMER; HIGH PHOTOSENSITIVITY AND EXCELLENT DURABILITY RICOH COMPANY, LTD. (JP) 1999-06-08 US disclosed
US-5871876-A CHARGE TRANSPORT MATERIAL WITH POLYCARBONATE STRUCTURE HAVING TRIARYLAMINO GROUPS; PHTHALOCYANINE CHARGE GENERATING COMPOUND; WEAR RESISTANCE; COPIERS RICOH COMPANY, LTD. (JP) 1999-02-16 US disclosed
US-5853935-A Electrophotographic photoconductor RICOH COMPANY, LTD. (JP) 1998-12-29 US disclosed
US-5846680-A Electrophotographic photoconductor and aromatic polycarbonate resin for use therein RICOH COMPANY, LTD. (JP) 1998-12-08 US disclosed
US-5840454-A Aromatic polycarbonate and electrophotographic photosensitive medium using same RICOH COMPANY, LTD. (JP) 1998-11-24 US disclosed
US-5789128-A Electrophotographic photoconductor and aromatic polycarbonate resin for use therein RICOH COMPANY, LTD. (JP) 1998-08-04 US disclosed
US-5723243-A MULTILAYER ELECTROCONDUCTOR SUPPORTS WITH AROMATIC POLYCARBONATES RICOH COMPANY, LTD. (JP) 1998-03-03 US disclosed