Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | CD69 | Q07108 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PYGB | P11216 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | OGA | O60502 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16393015 | 1.00 | ALDH1A1 (0.53) | ALDH1A1THRBMAPK1CD69SMN1; SMN2 | |
| SCHEMBL28832478 | 0.86 | ALDH1A1 (0.53) | ALDH1A1THRBMAPK1CD69SMN1; SMN2 | |
| SCHEMBL26623157 | 0.86 | ALDH1A1 (0.52) | ALDH1A1THRBMAPK1CD69SMN1; SMN2 | |
| SCHEMBL19350518 | 0.86 | ALDH1A1 (0.52) | ALDH1A1THRBMAPK1CD69SMN1; SMN2 | |
| SCHEMBL12936319 | 0.83 | ALDH1A1 (0.58) | ALDH1A1THRBMAPK1CD69SMN1; SMN2 | |
| SCHEMBL17771655 | 0.83 | ALDH1A1 (0.58) | ALDH1A1THRBMAPK1CD69SMN1; SMN2 | |
| N-Acetylglucosamine SCHEMBL29459148 | 0.82 | MAPK1 (0.64) | ALDH1A1THRBMAPK1CD69SMN1; SMN2 | |
| N-Acetylglucosamine SCHEMBL28646062 | 0.82 | MAPK1 (0.64) | ALDH1A1THRBMAPK1CD69SMN1; SMN2 | |
| N-Acetylglucosamine SCHEMBL30994851 | 0.82 | MAPK1 (0.64) | ALDH1A1THRBMAPK1CD69SMN1; SMN2 | |
| N-Acetylglucosamine SCHEMBL17201981 | 0.82 | MAPK1 (0.64) | ALDH1A1THRBMAPK1CD69SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8058053-B2 | Modification of protein glycosylation in methylotrophic yeast | VIB, VZW (BE) | 2011-11-15 | — | — | US | disclosed |
| US-20090263863-A1 | MODIFICATION OF PROTEIN GLYCOSYLATION IN METHYLOTROPHIC YEAST | VIB, VZW (BE) | 2009-10-22 | — | — | US | disclosed |
| US-7507573-B2 | Modification of protein glycosylation in methylotrophic yeast | VIB, VZW (BE) | 2009-03-24 | — | — | US | disclosed |
| EP-1706480-A4 | MODIFICATION OF PROTEIN GLYCOSYLATION IN METHYLOTROPHIC YEAST | RES CORP TECHNOLOGIES INC (US) | 2007-06-13 | — | — | EP | disclosed |
| EP-1706480-A1 | MODIFICATION OF PROTEIN GLYCOSYLATION IN METHYLOTROPHIC YEAST | Research Corporation Technologies, Inc (US) | 2006-10-04 | — | — | EP | disclosed |
| WO-2005049807-A1 | MODIFICATION OF PROTEIN GLYCOSYLATION IN METHYLOTROPHIC YEAST | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 2005-06-02 | — | — | WO | disclosed |
| US-20050106664-A1 | Modification of protein glycosylation in methylotrophic yeast | VIB, VZW (BE) | 2005-05-19 | — | — | US | disclosed |