SCHEMBL1324980

SCHEMBL1324980

C#Cc1ncccn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13730699 0.79 HDAC8 (0.34)
SCHEMBL15870986 0.72 HDAC8 (0.39)
Propyne SCHEMBL4555609 0.69 HDAC8 (0.34)
SCHEMBL24435974 0.69 HDAC8 (0.38)
SCHEMBL23235300 0.67
SCHEMBL17321845 0.67
SCHEMBL534717 0.67
SCHEMBL2852858 0.67
SCHEMBL151679 0.67
SCHEMBL28061488 0.67 CLK4 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 344 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250122132-A1 NITRIFICATION INHIBITORS LINCOLN UNIVERSITY (NZ) 2025-04-17 US claimed
EP-3990417-B1 IMPROVEMENTS IN AND RELATING TO NITRIFICATION INHIBITORS LINCOLN UNIV (NZ) 2024-03-27 EP claimed
EP-4339261-A2 IMPROVEMENTS IN AND RELATING TO NITRIFICATION INHIBITORS Lincoln University (NZ) 2024-03-20 EP claimed
US-20230202941-A1 NITRIFICATION INHIBITORS LINCOLN UNIVERSITY (NZ) 2023-06-29 US claimed
CN-115867525-A Improvements in and relating to nitrification inhibitors 林肯大学 2023-03-28 CN claimed
US-11578013-B2 Nitrification inhibitors LINCOLN UNIVERSITY (NZ) 2023-02-14 US claimed
US-20220153655-A1 NITRIFICATION INHIBITORS LINCOLN UNIVERSITY (NZ) 2022-05-19 US claimed
EP-3990417-A1 IMPROVEMENTS IN AND RELATING TO NITRIFICATION INHIBITORS Lincoln University (NZ) 2022-05-04 EP claimed
EP-2445897-B1 NOVEL INDAZOLE ARYLAMIDES AS P2X3 AND/OR P2X2/3 ANTAGONISTS HOFFMANN LA ROCHE (CH) 2014-03-19 EP claimed
CN-101089010-B 2' -fluoronucleosides EMORY UNIVERSITY (US) 2011-12-14 CN claimed
EP-1768978-B1 2,4,6-TRISUBSTITUTED PYRIMIDINES AS PHOSPHOTIDYLINOSITOL (PI) 3-KINASE INHIBITORS AND THEIR USE IN THE TREATMENT OF CANCER ASTRAZENECA AB (SE) 2008-07-09 EP claimed
EP-1109787-B1 ARYLPIPERAZINES AND THEIR USE AS METALLOPROTEINASE INHIBITING AGENTS (MMP) ASTRAZENECA AB (SE) 2006-05-17 EP claimed
US-20050014711-A1 Composition, formulations &amp; methods for prevention and treatment of diseases and conditions associated with bronchoconstriction, allergy(ies) and inflammation NYCE JONATHAN W (US) 2005-01-20 US claimed
US-6825174-B2 MIXTURE OF SURFACTANT AND NUCLEIC ACIDS EAST CAROLINA UNIVERSITY 2004-11-30 US claimed
EP-1177201-A1 4'-C-ETHYNYL PYRIMIDINE NUCLEOSIDES YAMASA CORPORATION (JP) 2002-02-06 EP claimed
WO-2000069876-A1 4'-C-ETHYNYL PYRIMIDINE NUCLEOSIDES YAMASA CORPORATION (JP) 2000-11-23 WO claimed
EP-0589445-B1 Renin Inhibiting N-(2-Amino-2-oxoethyl)Butanediamide Derivatives BIO MEGA BOEHRINGER INGELHEIM (CA) 1997-01-15 EP claimed
CN-116507617-B 1- (2- (4-Cyclopropyl-1H-1, 2, 3-triazol-1-yl) acetyl) -4-hydroxypyrrolidine-2-carboxamide derivatives as VHL inhibitors 基因泰克公司 2026-05-22 CN disclosed
EP-0637965-A1 ENHANCED TRIPLE-HELIX AND DOUBLE-HELIX FORMATION WITH OLIGOMERS CONTAINING MODIFIED PYRIMIDINES GILEAD SCIENCES, INC. (US) 1995-02-15 EP disclosed
WO-1993010820-A1 ENHANCED TRIPLE-HELIX AND DOUBLE-HELIX FORMATION WITH OLIGOMERS CONTAINING MODIFIED PYRIMIDINES GILEAD SCIENCES, INC. (US) 1993-06-10 WO disclosed